Suzuki N, Kano M
J Cell Physiol. 1977 Dec;93(3):383-8. doi: 10.1002/jcp.1040930309.
In the presence of tetraethylammonium or barium ions, the larval muscle fibers of Drosophila melanogaster were found to produce an all-or-none action potential operated by the calcium channels. The development of this distinctive membrane property during the maturation of muscle cells was studied by measuring the maximum rate of rise of the action potential in the larval muscle fibers at different stages of development from the sixteenth to ninety-sixth hours after hatching. The value increased significantly with age until a peak was reached at the sixty-fourth hour, although it became lower again as puparium formation neared at about the ninety-sixth hour. This suggests that during larval development the muscle fibers develop the ability to generate an action potential due to an inward current through the calcium channels, although the ability became lower at the later stage of larval development.
在存在四乙铵或钡离子的情况下，发现黑腹果蝇的幼虫肌纤维会产生由钙通道控制的全或无动作电位。通过测量孵化后第16至96小时不同发育阶段幼虫肌纤维动作电位的最大上升速率，研究了这种独特膜特性在肌肉细胞成熟过程中的发育情况。该值随年龄显著增加，直到第64小时达到峰值，尽管在大约第96小时化蛹期临近时又再次降低。这表明在幼虫发育过程中，肌纤维由于通过钙通道的内向电流而发展出产生动作电位的能力，尽管在幼虫发育后期该能力降低。
