利福霉素衍生物对三种核苷酸聚合酶的抑制作用。
Inhibition of three nucleotide polymerases by rifamycin derivatives.
作者信息
Thompson F M, Tischler A N, Adams J, Calvin M
出版信息
Proc Natl Acad Sci U S A. 1974 Jan;71(1):107-9. doi: 10.1073/pnas.71.1.107.
Abstract
It is possible to design rifamycin derivatives which can distinguish between viral RNA-instructed DNA polymerase and other nucleotide polymerases.
摘要
设计出能够区分病毒RNA指导的DNA聚合酶和其他核苷酸聚合酶的利福霉素衍生物是有可能的。
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本文引用的文献
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Actions of the rifamycins.利福霉素的作用。
Bacteriol Rev. 1971 Sep;35(3):290-309. doi: 10.1128/br.35.3.290-309.1971.
2
The rifamycins--relation of chemical structure and action on RNA polymerase.利福霉素——化学结构与对RNA聚合酶作用的关系
Biochim Biophys Acta. 1969 May 20;182(1):24-9. doi: 10.1016/0005-2787(69)90516-4.
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Synthesis of some rifamycin derivatives as inhibitors of an RNA-instructed DNA polymerase function.一些利福霉素衍生物作为RNA指导的DNA聚合酶功能抑制剂的合成。
J Med Chem. 1973 Oct;16(10):1071-5. doi: 10.1021/jm00268a001.
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Mechanism of action of a rifamycin derivative (AF-013) which is active on the nucleic acid polymerases insensitive to rifampicin.一种对利福平不敏感的核酸聚合酶有活性的利福霉素衍生物（AF-013）的作用机制
Biochem Biophys Res Commun. 1972 Dec 4;49(5):1263-71. doi: 10.1016/0006-291x(72)90604-3.
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Animal DNA-dependent RNA polymerases. 4. Studies on inhibition by rifamycin derivatives.动物DNA依赖性RNA聚合酶。4. 利福霉素衍生物抑制作用的研究。
Eur J Biochem. 1972 Jul 13;28(2):291-300. doi: 10.1111/j.1432-1033.1972.tb01913.x.
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3-Cyclic amine derivatives of rifamycin: strong inhibitors of the DNA polymerase activity of RNA tumor viruses.利福霉素的3-环胺衍生物：RNA肿瘤病毒DNA聚合酶活性的强效抑制剂。
Proc Natl Acad Sci U S A. 1972 May;69(5):1294-8. doi: 10.1073/pnas.69.5.1294.
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Inhibitors of the RNA and DNA dependent polymerase activities of RNA tumour viruses.RNA肿瘤病毒的RNA和DNA依赖性聚合酶活性抑制剂。
Nat New Biol. 1971 Jan 27;229(4):111-4. doi: 10.1038/newbio229111a0.
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RNA-dependent DNA polymerase in virions of Rous sarcoma virus.劳氏肉瘤病毒病毒粒子中的RNA依赖性DNA聚合酶。
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Nature. 1970 Jun 27;226(5252):1209-11. doi: 10.1038/2261209a0.
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