Robert M S, Smith R G, Gallo R C, Sarin P S, Abrell J W
Science. 1972 May 19;176(4036):798-800. doi: 10.1126/science.176.4036.798.
Two DNA polymerases purified from normal human lymphocytes are distinguishable from the viral reverse transcriptases of avian myeloblastosis virus and Mason-Pfizer monkey virus by their relative affinity for select templates. In this respect, the activity of the two normal human lymphocyte polymerases closely resembles the activity of Escherichia coli DNA polymerase 1. The viral and cellular DNA polymerases are equally active with the nonspecific template, poly(rA) . poly(dT). Criteria for distinguishing the activity of viral reverse transcriptase are discussed.
从正常人淋巴细胞中纯化出的两种DNA聚合酶，通过它们对特定模板的相对亲和力，可与禽成髓细胞瘤病毒和马森 - Pfizer猴病毒的病毒逆转录酶区分开来。在这方面，两种正常人淋巴细胞聚合酶的活性与大肠杆菌DNA聚合酶1的活性非常相似。病毒和细胞DNA聚合酶对非特异性模板聚（rA）·聚（dT）的活性相同。文中讨论了区分病毒逆转录酶活性的标准。
