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透析器的细菌污染。不同透析液混合系统的临床、细菌学及扫描电子显微镜评估。

Bacteriological contamination of dialyzers. Clinical, bacteriological and scanning electron-microscopic evaluation of different dialysate mixing systems.

作者信息

Jans H, Bretlau P, Nielsen B

出版信息

Nephron. 1978;20(1):10-7. doi: 10.1159/000181190.

DOI:10.1159/000181190
PMID:413062
Abstract

Membranes from Gambro Lundia Nova dialyzers were investigated for presence of bacteria after hemodialysis with centrally and peripherally mixed dialysate. Centrally mixed dialysate was found contaminated with Pseudomonas aeruginosa, and bacterial cultures as well as electron scanning micrographs showed the presence of these bacteria on the dialysate side as well as on the blood side of membranes from dialyzers perfused with this dialysate during hemodialysis. No bacteria were found on membranes used with peripherally mixed dialysate, in which very few bacteria were found. Despite this the frequency of febrile episodes in patients submitted to hemodialysis with the two different dialysate mixing systems showed no significant difference in our material.

摘要

对金宝Lundia Nova透析器的膜进行了研究,以检测在使用中心混合和外周混合透析液进行血液透析后是否存在细菌。发现中心混合透析液被铜绿假单胞菌污染,细菌培养以及电子扫描显微镜照片显示,在血液透析期间使用这种透析液灌注的透析器的膜的透析液侧和血液侧均存在这些细菌。在外周混合透析液使用的膜上未发现细菌,在外周混合透析液中发现的细菌极少。尽管如此,在我们的研究材料中,使用两种不同透析液混合系统进行血液透析的患者中发热发作的频率没有显著差异。

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Bacteriological contamination of dialyzers. Clinical, bacteriological and scanning electron-microscopic evaluation of different dialysate mixing systems.透析器的细菌污染。不同透析液混合系统的临床、细菌学及扫描电子显微镜评估。
Nephron. 1978;20(1):10-7. doi: 10.1159/000181190.
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Transfer of cytokine-inducing bacterial products across hemodialyzer membranes in the presence of plasma or whole blood.在血浆或全血存在的情况下,细胞因子诱导性细菌产物通过血液透析器膜的转运。
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引用本文的文献

1
Flavobacterium multivorum septicemia in a hemodialyzed patient.一名接受血液透析患者的多食黄杆菌败血症
J Clin Microbiol. 1984 Apr;19(4):568-9. doi: 10.1128/jcm.19.4.568-569.1984.
2
Prevalence of nontuberculous mycobacteria in water supplies of hemodialysis centers.血液透析中心供水系统中非结核分枝杆菌的患病率。
Appl Environ Microbiol. 1988 Dec;54(12):3122-5. doi: 10.1128/aem.54.12.3122-3125.1988.