Thomas S R, Gelfand M J, Kereiakes J G, Ascoli F A, Maxon H R, Saenger E L, Feller P A, Sodd V J, Paras P
Radiology. 1978 Jan;126(1):193-5. doi: 10.1148/126.1.193.
The spatial temporal distribution of radionuclides in children may differ greatly from that accepted for adults. Following injection of a bone-seeking agent (99mTc-EHDP), radioactivity in the metaphyseal growth complexes of the distal femur and proximal tibia was quantitated in a series of children 4 to 16 years of age, using a gamma camera/computer system. The dose to the growth plate was fount to range from 0.8 to 4.7 rads when adjusted to an administered activity of 200 muCi/kg, compared to approximately 0.6 rad to the adult skeleton for a corresponding study.
儿童体内放射性核素的时空分布可能与成人的公认分布有很大差异。在注射骨显像剂(99mTc-EHDP)后,使用γ相机/计算机系统对一系列4至16岁儿童的股骨远端和胫骨近端干骺端生长复合体中的放射性进行了定量分析。当调整为200μCi/kg的给药活度时,生长板所接受的剂量为0.8至4.7拉德,而相应研究中成人骨骼所接受的剂量约为0.6拉德。