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99mTc 磷酸盐化合物用于儿童骨闪烁扫描术的辐射剂量(作者译)

[The radiation dose to children bone scintigraphy with 99mTc-phosphate compounds (author's transl)].

作者信息

Eissner D, Wolf R

出版信息

Rofo. 1980 Mar;132(3):331-5. doi: 10.1055/s-2008-1056573.

Abstract

In order to determine the radiation dose to children during bone scintigraphy, distribution and excretion measurements on 99mTc-pyrophosphate and 99mTc-diphosphonate were carried out in rats, piglets, children and adults. Because of the more intensive bone metabolism in children, uptake of 43 to 47% is higher than in adults, in whom uptake in the skeleton reaches 33 to 36%. Assuming homogenous distribution of uptake, radiation dose to the skeleton in children of the ages investigated was 51 to 55 mrd per mCi. Bearing in mind the non-homogeneous distribution in the juvenile skeleton, radiation dose at growth point reaches 85 to 95 mrd per mCi.

摘要

为了确定骨闪烁扫描期间儿童所接受的辐射剂量,我们对大鼠、仔猪、儿童和成人进行了99m锝-焦磷酸盐和99m锝-二膦酸盐的分布及排泄测量。由于儿童的骨代谢更为活跃,其摄取量为43%至47%,高于成人,成人骨骼的摄取量为33%至36%。假设摄取均匀分布,在所研究年龄的儿童中,每毫居里骨骼所接受的辐射剂量为51至55毫雷姆。考虑到青少年骨骼的分布不均匀,生长点处的辐射剂量达到每毫居里85至95毫雷姆。

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