微管之间的桥接结构。
Bridges between microtubules.
作者信息
McIntosh J R
出版信息
J Cell Biol. 1974 Apr;61(1):166-87. doi: 10.1083/jcb.61.1.166.
Abstract
Bridges between microtubules have been studied with the electron microscope in the axostyle of Saccinobaculus and in various tubule systems of chicken testis, including the helix of tubules surrounding the elongating spermatid nucleus and the flagellum of the sperm tail. In addition to the previously described periodic bridges, evidence is presented that nonperiodic bridges exist between certain tubules. An analysis of axial spacing between adjacent nonperiodic bridges suggests that these structures are attached to periodic binding sites on the microtubule wall, but that not all the binding sites are filled. The bridges appear nonperiodic as a result of random occupancy of some fraction of the periodic sites. The distribution of these binding sites is related to the substructure of the microtubule wall as seen with negative staining and optical diffraction.
摘要
利用电子显微镜对微管间的桥接进行了研究，研究对象包括袋形杆菌的轴柱以及鸡睾丸的各种小管系统，其中包括围绕伸长的精子细胞核的小管螺旋结构和精子尾部的鞭毛。除了先前描述的周期性桥接外，还提供了证据表明某些小管之间存在非周期性桥接。对相邻非周期性桥接之间轴向间距的分析表明，这些结构附着在微管壁上的周期性结合位点上，但并非所有结合位点都被占据。由于周期性位点的一部分被随机占据，这些桥接看起来是非周期性的。这些结合位点的分布与用负染色和光学衍射观察到的微管壁亚结构有关。
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