Lalonde J M, Ghadially F N
Virchows Arch B Cell Pathol. 1977 Nov 3;25(3):221-32. doi: 10.1007/BF02889435.
Haematomas were produced in rabbits by subcutaneous injection of autologous blood. Clotting and marked lysis of erythrocytes was noted in these haematomas, but there was no evidence of fragmentation of erythrocytes prior to or after ingestion by macrophages as has been reported in other sites such as the peritoneal cavity and the joint cavity. The phagocytosis of intact erythrocytes, lysed erythrocytes and haemoglobin led to the formation of three main types of lysosomal bodies; (1) myelinosomes containing whorled osmiophilic membranes, (2) siderosomes containing haemosiderin, and (3) myelinosiderosomes containing a mixture of osmiophilic membranes and haemosiderin.
通过皮下注射自体血液在兔子身上制造血肿。在这些血肿中观察到红细胞的凝血和显著溶解，但没有证据表明红细胞在被巨噬细胞吞噬之前或之后发生破碎，而在其他部位如腹腔和关节腔已有相关报道。完整红细胞、溶解红细胞和血红蛋白的吞噬作用导致形成三种主要类型的溶酶体；（1）含有涡状嗜锇性膜的髓磷脂小体，（2）含有含铁血黄素的含铁小体，以及（3）含有嗜锇性膜和含铁血黄素混合物的髓磷脂含铁小体。
