布美他尼用于婴儿心力衰竭
Bumetanide in heart failure in infancy.
作者信息
Ward O C, Lam L K
出版信息
Arch Dis Child. 1977 Nov;52(11):877-82. doi: 10.1136/adc.52.11.877.
Abstract
The effect of bumetanide in infants with congenital heart disease presenting with cardiac failure was studied. The study was divided into acute (3 days) and long-term (mean 10.5 weeks) cases. A total of 12 male infants was included in the acute study and 13 cases were evaluated in the long-term study. The dose used in the acute study (0.015 mg/kg) was suboptimal; notwithstanding it was found to cause significant natriuresis and chloruresis. Bumetanide in doses varying in different infants from as little as 0.015 mg/kg on alternate days to as much as 0.10 mg/kg daily was shown to be an effective diuretic for long-term use. No side effects were observed in either study.
摘要
研究了布美他尼对患有心力衰竭的先天性心脏病婴儿的影响。该研究分为急性（3天）和长期（平均10.5周）病例。急性研究共纳入12名男婴，长期研究评估了13例。急性研究中使用的剂量（0.015mg/kg）并非最佳；尽管如此，仍发现它可引起显著的利钠和利尿作用。布美他尼的剂量在不同婴儿中有所不同，从低至隔日0.015mg/kg到高达每日0.10mg/kg，被证明是一种有效的长期利尿剂。两项研究均未观察到副作用。
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1
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Proc Soc Exp Biol Med. 1964 Jan;115:29-32.
2
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J Pediatr. 1969 Jul;75(1):139-52. doi: 10.1016/s0022-3476(69)80116-2.
3
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Br Med J. 1969 Mar 22;1(5646):751-2. doi: 10.1136/bmj.1.5646.751.
4
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5
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Br Med J. 1971 Feb 20;1(5746):437-8. doi: 10.1136/bmj.1.5746.437.
6
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J Med Chem. 1971 May;14(5):432-9. doi: 10.1021/jm00287a014.
7
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