绵羊血清共凝集物质的特性
Characteristics of the conglutinating substance of sheep serum.
作者信息
Mittal K R, Ingram D G
出版信息
Can J Comp Med. 1974 Jul;38(3):292-7.
The conglutinating factor in sheep serum was characterized utilizing its ability to react with sensitized erythrocytes which had been alexinated with horse complement. The conglutinating substance in sheep serum was inactivated by the action of 2-mercaptoethanol, did not require calcium ions for its activity, was not inhibited by N-acetyl-D-glucosamine or L-fucose sugars and did not react directly with zymosan. All these activities distinguish this serum factor from bovine conglutinin. These data show that the conglutinating factor in sheep serum is an immunoconglutinin. Reactivity of sheep immunoconglutinin with both heterologous and autologous complement was demonstrated.
利用绵羊血清中的胶固素因子与已用马补体进行过阿列克辛处理的致敏红细胞发生反应的能力，对其进行了特性鉴定。绵羊血清中的胶固物质会被2-巯基乙醇的作用所灭活，其活性不需要钙离子，不受N-乙酰-D-葡萄糖胺或L-岩藻糖的抑制，并且不与酵母聚糖直接发生反应。所有这些特性将这种血清因子与牛胶固素区分开来。这些数据表明，绵羊血清中的胶固素因子是一种免疫胶固素。已证实绵羊免疫胶固素与异种和自身补体均有反应性。
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