小鼠染色体中的着丝粒融合、卫星DNA和DNA极性
Centric fusion, satellite DNA, and DNA polarity in mouse chromosomes.
作者信息
Lin M S, Davidson R L
出版信息
Science. 1974 Sep 27;185(4157):1179-81. doi: 10.1126/science.185.4157.1179.
PMID:4137570
Abstract
A fluorescent staining technique has demonstrated a contralateral arrangement of fluorescent spots in the centromeric region of mouse metacentric chromosomes which have resulted from centric fusion. The results suggest that centric fusion involves the maintenance of DNA polaritv through the centromere and that the thymidine-rich chain of satellite DNA in the centromeric region is associated with the same DNA chain in every mouse autosome.
摘要
一种荧光染色技术已证明，在因着丝粒融合而产生的小鼠中着丝粒染色体的着丝粒区域，荧光斑点呈对侧排列。结果表明，着丝粒融合涉及通过着丝粒维持DNA极性，并且着丝粒区域富含胸腺嘧啶的卫星DNA链与每一条小鼠常染色体中的同一条DNA链相关联。
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