• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

传染性法氏囊病病毒的结构

Structure of infectious bursal disease virus.

作者信息

Hirai K, Shimakura S

出版信息

J Virol. 1974 Oct;14(4):957-64. doi: 10.1128/JVI.14.4.957-964.1974.

DOI:10.1128/JVI.14.4.957-964.1974
PMID:4138194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC355603/
Abstract

Infectious bursal disease virus of chickens was purified, and its structure was examined by the negative-staining technique in the electron microscope. The buoyant density of infectious bursal disease virus in CsCl was found to be 1.34 g/cm(3). The morphological details suggest that the capsid of the virion consists of a single layer of 32 capsomeres arranged in 5:3:2 symmetry. The virion measured about 55 nm in diameter and had no envelope.

摘要

鸡传染性法氏囊病病毒被提纯，并运用电子显微镜中的负染技术对其结构进行了检测。结果发现，传染性法氏囊病病毒在氯化铯中的浮密度为1.34克/立方厘米。形态学细节表明，病毒粒子的衣壳由32个壳粒组成的单层结构，呈5:3:2对称排列。病毒粒子直径约为55纳米，无包膜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/f4a4574103be/jvirol00250-0267-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/66393aade458/jvirol00250-0263-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/66a688edb9d4/jvirol00250-0264-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/c1dfa20389af/jvirol00250-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/83b0b55ebe89/jvirol00250-0266-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/f4a4574103be/jvirol00250-0267-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/66393aade458/jvirol00250-0263-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/66a688edb9d4/jvirol00250-0264-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/c1dfa20389af/jvirol00250-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/83b0b55ebe89/jvirol00250-0266-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b2/355603/f4a4574103be/jvirol00250-0267-a.jpg

相似文献

1
Structure of infectious bursal disease virus.传染性法氏囊病病毒的结构
J Virol. 1974 Oct;14(4):957-64. doi: 10.1128/JVI.14.4.957-964.1974.
2
Infectious bursal disease agent: morphology by negative stain electron microscopy.
Arch Virol. 1975;48(1):63-73. doi: 10.1007/BF01320566.
3
Structural and growth characteristics of infectious bursal disease virus.传染性法氏囊病病毒的结构与生长特性
J Virol. 1976 Apr;18(1):227-34. doi: 10.1128/JVI.18.1.227-234.1976.
4
Infectious bursal disease virus: further characterization with evidence for a single-stranded RNA virus.传染性法氏囊病病毒：单链RNA病毒证据的进一步特征分析
Avian Dis. 1980 Apr-Jun;24(2):423-34.
5
Spontaneous degradation of reovirus capsid into subunits.呼肠孤病毒衣壳自发降解为亚基。
J Virol. 1971 Nov;8(5):805-8. doi: 10.1128/JVI.8.5.805-808.1971.
6
Further morphological characterization and structural proteins of infectious bursal disease virus.传染性法氏囊病病毒的进一步形态学特征及结构蛋白
J Virol. 1979 Oct;32(1):323-8. doi: 10.1128/JVI.32.1.323-328.1979.
7
Antigenically-related viruses associated with infectious bursal disease.
J Gen Virol. 1973 Sep;20(3):369-75. doi: 10.1099/0022-1317-20-3-369.
8
Proteinaceous virus-like particles from an isolate of Aspergillus flavus.
J Virol. 1974 Feb;13(2):532-4. doi: 10.1128/JVI.13.2.532-534.1974.
9
Gamma ray-induced small plaque mutants of western equine encephalitis virus.γ射线诱导的西部马脑炎病毒小斑块突变体
J Virol. 1973 Dec;12(6):1568-78. doi: 10.1128/JVI.12.6.1568-1578.1973.
10
Defective virions of reovirus.呼肠孤病毒的缺陷病毒粒子
J Virol. 1970 Aug;6(2):226-36. doi: 10.1128/JVI.6.2.226-236.1970.

引用本文的文献

1
Assessing the antigenicity of different VP3 regions of infectious bursal disease virus in chickens from South Brazil.评估来自巴西南部的鸡传染性法氏囊病病毒不同 VP3 区的抗原性。
BMC Vet Res. 2021 Jul 30;17(1):259. doi: 10.1186/s12917-021-02956-0.
2
Research Progress on MicroRNAs Involved in the Regulation of Chicken Diseases.参与鸡病调控的微小RNA的研究进展
J Poult Sci. 2020 Jan 25;57(1):7-17. doi: 10.2141/jpsa.0190073.
3
Identification of Chicken CD74 as a Novel Cellular Attachment Receptor for Infectious Bursal Disease Virus in Bursa B Lymphocytes.

本文引用的文献

1
REOVIRUSES. II. STRUCTURE AND COMPOSITION OF THE VIRION.呼肠孤病毒。二、病毒粒子的结构与组成。
J Bacteriol. 1965 Jun;89(6):1548-56. doi: 10.1128/jb.89.6.1548-1556.1965.
2
SENSITIVITY OF BLUETONGUE VIRUS TO ETHER AND SODIUM DEOXYCHOLATE.蓝舌病毒对乙醚和脱氧胆酸钠的敏感性
Proc Soc Exp Biol Med. 1965 Apr;118:1006-9. doi: 10.3181/00379727-118-30030.
3
FINE STRUCTURE OF REOVIRUS TYPE 2.2型呼肠孤病毒的精细结构
鉴定鸡 CD74 为传染性法氏囊病病毒在法氏囊 B 淋巴细胞中的新型细胞附着受体。
J Virol. 2020 Jan 6;94(2). doi: 10.1128/JVI.01712-19.
4
Macrophage Migration Inhibitory Factor Triggers Inflammatory Responses During Very Virulent Infectious Bursal Disease Virus Infection.巨噬细胞迁移抑制因子在超强毒传染性法氏囊病病毒感染期间引发炎症反应。
Front Microbiol. 2019 Oct 1;10:2225. doi: 10.3389/fmicb.2019.02225. eCollection 2019.
5
Efficient self-assembly and protective efficacy of infectious bursal disease virus-like particles by a recombinant baculovirus co-expressing precursor polyprotein and VP4.通过共表达前体多聚蛋白和VP4的重组杆状病毒实现传染性法氏囊病病毒样颗粒的高效自组装及保护效力
Virol J. 2015 Oct 26;12:177. doi: 10.1186/s12985-015-0403-4.
6
Effects of temperature, relative humidity, absolute humidity, and evaporation potential on survival of airborne Gumboro vaccine virus.温度、相对湿度、绝对湿度和蒸发潜能对空气中传染性法氏囊病疫苗病毒存活的影响。
Appl Environ Microbiol. 2012 Feb;78(4):1048-54. doi: 10.1128/AEM.06477-11. Epub 2011 Dec 9.
7
Detection of infectious bursal disease virus (IBDV) genome in free-living pigeon and guinea fowl in Africa suggests involvement of wild birds in the epidemiology of IBDV.在非洲自由生活的鸽子和珍珠鸡中检测到传染性法氏囊病病毒（IBDV）基因组，这表明野生鸟类参与了IBDV的流行病学传播。
Virus Genes. 2008 Jun;36(3):521-9. doi: 10.1007/s11262-008-0219-z. Epub 2008 Mar 15.
8
Identification and molecular characterization of the RNA polymerase-binding motif of infectious bursal disease virus inner capsid protein VP3.传染性法氏囊病病毒内衣壳蛋白VP3的RNA聚合酶结合基序的鉴定与分子特征分析
J Virol. 2003 Feb;77(4):2459-68. doi: 10.1128/jvi.77.4.2459-2468.2003.
9
VP1, the putative RNA-dependent RNA polymerase of infectious bursal disease virus, forms complexes with the capsid protein VP3, leading to efficient encapsidation into virus-like particles.传染性法氏囊病病毒假定的依赖RNA的RNA聚合酶VP1与衣壳蛋白VP3形成复合物，从而有效地包装成病毒样颗粒。
J Virol. 1999 Aug;73(8):6973-83. doi: 10.1128/JVI.73.8.6973-6983.1999.
10
A second form of infectious bursal disease virus-associated tubule contains VP4.传染性法氏囊病病毒相关小管的第二种形式含有VP4。
J Virol. 1997 Nov;71(11):8879-85. doi: 10.1128/JVI.71.11.8879-8885.1997.
J Bacteriol. 1965 Apr;89(4):1140-4. doi: 10.1128/jb.89.4.1140-1144.1965.
4
THERMAL INACTIVATION OF BLUE TONGUE VIRUS.蓝舌病毒的热灭活
Arch Gesamte Virusforsch. 1963 Aug 26;13:499-510. doi: 10.1007/BF01267793.
5
Physical principles in the construction of regular viruses.常规病毒构建中的物理原理。
Cold Spring Harb Symp Quant Biol. 1962;27:1-24. doi: 10.1101/sqb.1962.027.001.005.
6
The morphology of reovirus.呼肠孤病毒的形态学
Virology. 1962 Aug;17:503-10. doi: 10.1016/0042-6822(62)90149-6.
7
Physicochemical properties of the infectious bursal agent (IBA).
Avian Dis. 1967 Aug;11(3):438-45.
8
Characterization of the infectious bursal agent.
Poult Sci. 1969 Nov;48(6):2102-9. doi: 10.3382/ps.0482102.
9
Sensitivity of bluetongue virus to lipid solvents, trypsin and pH changes and its serological relationship to arboviruses.蓝舌病毒对脂溶剂、胰蛋白酶和pH变化的敏感性及其与虫媒病毒的血清学关系。
J Hyg (Lond). 1966 Sep;64(3):339-46. doi: 10.1017/s0022172400040614.
10
[Multiplication of the causative agent of infectious bursitis in young fowls (Gumboro disease) in chick embryo kidney cell cultures].
Zentralbl Veterinarmed B. 1971 Jul;18(5):366-72.