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传染性法氏囊病病毒的结构与生长特性

Structural and growth characteristics of infectious bursal disease virus.

作者信息

Nick H, Cursiefen D, Becht H

出版信息

J Virol. 1976 Apr;18(1):227-34. doi: 10.1128/JVI.18.1.227-234.1976.

DOI:10.1128/JVI.18.1.227-234.1976
PMID:176463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC515542/
Abstract

The infectious bursal disease virus is not enveloped and has a diameter of 60 nm and a density of about 1.32 g/ml. It contains two pieces of single-stranded RNA with molecular weights close to 2 X 10(6). The capsid is made up of four major polypeptides with molecular weights of 110,000, 50,000, 35,000, and 25,000. The virus replicates in chicken embryo fibroblasts rather than in epitheloid cells. After an eclipse period of 4 h, virus production reaches a maximum about 12 h later. The virus has no structural or biological similarities with defined avian reoviruses, and it cannot be classified in one of the established taxonomic groups.

摘要

传染性法氏囊病病毒无包膜,直径为60纳米,密度约为1.32克/毫升。它含有两条单链RNA,分子量接近2×10⁶。衣壳由四种主要多肽组成,分子量分别为110,000、50,000、35,000和25,000。该病毒在鸡胚成纤维细胞中复制,而非在类上皮细胞中复制。在4小时的隐蔽期后,约12小时后病毒产量达到最大值。该病毒与已确定的禽呼肠孤病毒在结构或生物学上无相似之处,无法归类于已有的分类学组中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/053b4b7c1697/jvirol00220-0249-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/3c3065205a2f/jvirol00220-0245-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/d315a45b5cd0/jvirol00220-0247-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/c1647f04af24/jvirol00220-0248-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/053b4b7c1697/jvirol00220-0249-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/3c3065205a2f/jvirol00220-0245-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/d315a45b5cd0/jvirol00220-0247-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/c1647f04af24/jvirol00220-0248-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db28/515542/053b4b7c1697/jvirol00220-0249-a.jpg

相似文献

1
Structural and growth characteristics of infectious bursal disease virus.传染性法氏囊病病毒的结构与生长特性
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引用本文的文献

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Front Microbiol. 2021 Jun 11;12:678563. doi: 10.3389/fmicb.2021.678563. eCollection 2021.
2
Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals.植物源兽用疫苗的生产及其在动物疾病预防中的应用
Adv Virol. 2015;2015:936940. doi: 10.1155/2015/936940. Epub 2015 Aug 13.
3
Molecular determinants of virulence, cell tropism, and pathogenic phenotype of infectious bursal disease virus.

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