Kjellin K G, Stibler H
J Neurol Neurosurg Psychiatry. 1974 Oct;37(10):1128-32. doi: 10.1136/jnnp.37.10.1128.
The protein patterns found on isoelectric focusing and quantitative paper electrophoresis of cerebrospinal fluid were studied in three patients with spasmodic torticollis. Very alkaline end fractions were found on isoelectric focusing in the CSF-gammaglobulin region in each case. Alkaline end fractions in the CSF-gammaglobulin region with similar or same isoelectric points have also been observed in other extrapyramidal disorders, particularly Huntington's chorea, and in other neurological diseases, especially in multiple sclerosis. It has to be shown if these alkalline end fractions consist of the same or different compounds, conceivable constituents being mentioned. Examination of the CSF-protein pattern might help to distinguish organic from hysterical torticollis.
对3例痉挛性斜颈患者脑脊液在等电聚焦和定量纸电泳中发现的蛋白质图谱进行了研究。在每种情况下，于脑脊液γ球蛋白区域的等电聚焦中均发现了极碱性的末端组分。在其他锥体外系疾病，特别是亨廷顿舞蹈病，以及其他神经疾病，尤其是多发性硬化症中，也观察到了脑脊液γ球蛋白区域具有相似或相同等电点的碱性末端组分。必须确定这些碱性末端组分是否由相同或不同的化合物组成，并提及了可能的成分。脑脊液蛋白质图谱的检查可能有助于区分器质性斜颈和癔症性斜颈。
