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脑脊液tau-转铁蛋白。对674例神经系统疾病患者的等电聚焦研究。

The cerebrospinal fluid tau-transferrin. Isoelectric focusing study on 674 neurological patients.

作者信息

Rocchelli B, Poloni M, Delodovici M, Mazarello P, Cosi V

出版信息

Ital J Neurol Sci. 1980 Oct;1(4):251-5. doi: 10.1007/BF02336706.

Abstract

The frequency of the two tau-fractions in isoelectric focusing examination of cerebrospinal fluid proteins has been studied in 674 neurological patients. The double tau-fraction was found in 151 patients (22.4%); this finding was not characteristically associated with any particular disease, but its frequency was high in hereditary diseases (13 cases out of 30; 43.3%), mainly Charcot-Marie-Tooth's disease.

摘要

对674例神经系统疾病患者的脑脊液蛋白等电聚焦检查中两种tau组分的频率进行了研究。在151例患者(22.4%)中发现了双tau组分;这一发现与任何特定疾病均无特征性关联,但其在遗传性疾病中频率较高(30例中有13例;43.3%),主要是夏科-马里-图斯病。

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