Törnquist P, Alm A
Acta Physiol Scand. 1979 Jul;106(3):351-7. doi: 10.1111/j.1748-1716.1979.tb06409.x.
The glucose metabolism of the retina was studied in vivo, by determining glucose, oxygen and lactate a-v differences for choroidal and retinal blood in pigs at different levels of intraocular pressure. At normal intraocular pressure the choroidal a-v differences were 0.07 and 0.11 mmol/l for glucose and oxygen respectively. The corresponding figures for the retina were 0.44 and 2.15. At increased levels of intraocular pressure the choroidal and retinal glucose and choroidal oxygen a-v differences increased, thus at least partly compensating for reduced blood flow. A major part of the oxygen and glucose consumed by the retina was delivered by the choroid. The total amount of oxygen extracted from choroidal and retinal blood could only account for complete oxidation of 37% of the extracted glucose. The results obtained in determinations of lactate a-v differences indicate that part of the remaining glucose is used for anaerobic glycolysis.
通过测定不同眼压水平下猪脉络膜和视网膜血液中的葡萄糖、氧气和乳酸动静脉差值，对视网膜的葡萄糖代谢进行了体内研究。在正常眼压下，脉络膜葡萄糖和氧气的动静脉差值分别为0.07和0.11 mmol/l。视网膜的相应数值分别为0.44和2.15。在眼压升高时，脉络膜和视网膜的葡萄糖以及脉络膜氧气的动静脉差值增加，从而至少部分补偿了血流量的减少。视网膜消耗的大部分氧气和葡萄糖由脉络膜提供。从脉络膜和视网膜血液中提取的氧气总量仅能解释所提取葡萄糖37%的完全氧化。乳酸动静脉差值测定结果表明，剩余葡萄糖的一部分用于无氧糖酵解。
