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The role of cytochrome P-450 in the N-oxidation of individual amines.

作者信息

Uehleke H

出版信息

Drug Metab Dispos. 1973 Jan-Feb;1(1):299-313.

PMID:4149397
Abstract
摘要

相似文献

1
The role of cytochrome P-450 in the N-oxidation of individual amines.细胞色素P-450在单个胺类N-氧化中的作用。
Drug Metab Dispos. 1973 Jan-Feb;1(1):299-313.
2
Reduction of tertiary amine N-oxides by liver microsomal cytochrome P-450.肝脏微粒体细胞色素P-450对叔胺N-氧化物的还原作用。
Mol Pharmacol. 1976 Mar;12(2):322-34.
3
Interaction of aromatic nitro compounds with reduced hepatic microsomal cytochrome P-450.
Drug Metab Dispos. 1975 Jul-Aug;3(4):266-74.
4
Perinatal development of tertiary amine N-oxidation and NADPH cytochrome C reduction in rat liver microsomes.大鼠肝微粒体中叔胺N-氧化和NADPH细胞色素C还原的围产期发育。
Res Commun Chem Pathol Pharmacol. 1971 Nov;2(6):793-805.
5
[Qualitative changes in liver microsomes of phenobarbital-treated rabbits. Changes in spectral dissociation constants (Ks) of aniline and N-ethylaniline, in the apparent Michaelis constants (Km) for hydroxylation of these substrates, and in affinity of the enzymes involved for oxygen and carbon monoxide].[苯巴比妥处理家兔肝脏微粒体的定性变化。苯胺和N-乙基苯胺光谱解离常数（Ks）的变化、这些底物羟基化表观米氏常数（Km）的变化以及所涉及酶对氧和一氧化碳的亲和力变化]
Naunyn Schmiedebergs Arch Pharmakol. 1970;267(4):307-26.
6
Microsomal flavoprotein-catalyzed N-oxidation of arylamines.
Drug Metab Dispos. 1973 Jan-Feb;1(1):314-21.
7
[Change in the affinity of isolated liver microsomes for aniline, N-ethylaniline, oxygen, ethyl isocyanide and carbon monoxide by the treatment of young rabbits with phenobarbital].[用苯巴比妥处理幼兔对离体肝微粒体与苯胺、N-乙基苯胺、氧、乙基异氰化物和一氧化碳亲和力的影响]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):161-3.
8
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
Naunyn Schmiedebergs Arch Pharmacol. 1974;282(Suppl):suppl 282:R81.
9
Binding of nitrogen containing compounds to microsomal cytochromes.含氮化合物与微粒体细胞色素的结合。
Xenobiotica. 1971 Jul-Oct;1(4):507-20. doi: 10.3109/00498257109041519.
10
Interaction of oxygen and aromatic amines with hepatic microsomal mixed-function oxidase.氧与芳香胺与肝微粒体混合功能氧化酶的相互作用。
Biochim Biophys Acta. 1972 Jul 19;273(2):318-27. doi: 10.1016/0304-4165(72)90223-1.

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Studies into radiolytic decomposition of fluorine-18 labeled radiopharmaceuticals for positron emission tomography.用于正电子发射断层扫描的氟 - 18标记放射性药物的辐射分解研究。
Appl Radiat Isot. 2009 Jan;67(1):88-94. doi: 10.1016/j.apradiso.2008.08.015. Epub 2008 Sep 7.
2
The in vitro metabolism of N,N-dimethylaniline by guinea pig and rabbit tissue preparations.豚鼠和兔组织制剂对N，N-二甲基苯胺的体外代谢
Eur J Drug Metab Pharmacokinet. 1981;6(3):195-206. doi: 10.1007/BF03189489.
3
N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans.
Naunyn Schmiedebergs Arch Pharmacol. 1973;278(1):55-68. doi: 10.1007/BF00501863.
4
DDT and selected analogues as microsomal oxidase inducers in the mouse.滴滴涕及其某些类似物作为小鼠微粒体氧化酶诱导剂的研究
Arch Environ Contam Toxicol. 1975;3(4):426-36. doi: 10.1007/BF02220813.
5
Chloroperoxidase-catalysed oxidation of 4-chloroaniline to 4-chloronitrosobenze.氯过氧化物酶催化4-氯苯胺氧化为4-氯亚硝基苯。
Biochem J. 1978 Nov 1;175(2):353-60. doi: 10.1042/bj1750353b.
6
Influences of inducers and inhibitors of the microsomal monooxygenase system on the alkylating intensity of dimethylnitrosamine in mice.微粒体单加氧酶系统诱导剂和抑制剂对小鼠体内二甲基亚硝胺烷基化强度的影响。
J Cancer Res Clin Oncol. 1979 May 14;94(1):47-61. doi: 10.1007/BF00405349.
7
Studies on the mechanism of hepatic microsomal N-oxide formation. The role of cytochrome P-450 and mixed-function amine oxidase in the N-oxidation of NN-dimethylaniline.肝微粒体N-氧化形成机制的研究。细胞色素P-450和混合功能胺氧化酶在N,N-二甲基苯胺N-氧化中的作用。
Biochem J. 1977 Jun 15;164(3):487-96. doi: 10.1042/bj1640487.
8
A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo.标记的氟烷、三氯氟甲烷、氯仿和四氯化碳在体外和体内与肝脏蛋白质和脂质不可逆结合的比较研究。
Arch Toxicol. 1975 Dec 18;34(4):289-308. doi: 10.1007/BF00353849.