[Qualitative changes in liver microsomes of phenobarbital-treated rabbits. Changes in spectral dissociation constants (Ks) of aniline and N-ethylaniline, in the apparent Michaelis constants (Km) for hydroxylation of these substrates, and in affinity of the enzymes involved for oxygen and carbon monoxide]. - Suppr | 超能文献

[Qualitative changes in liver microsomes of phenobarbital-treated rabbits. Changes in spectral dissociation constants (Ks) of aniline and N-ethylaniline, in the apparent Michaelis constants (Km) for hydroxylation of these substrates, and in affinity of the enzymes involved for oxygen and carbon monoxide].

作者信息

Kröber F, Lange G, Mathes S, Mor G

出版信息

Naunyn Schmiedebergs Arch Pharmakol. 1970;267(4):307-26.

Abstract

摘要

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[Qualitative changes in liver microsomes of phenobarbital-treated rabbits. Changes in spectral dissociation constants (Ks) of aniline and N-ethylaniline, in the apparent Michaelis constants (Km) for hydroxylation of these substrates, and in affinity of the enzymes involved for oxygen and carbon monoxide].

Naunyn Schmiedebergs Arch Pharmakol. 1970;267(4):307-26.

2

[Change in the affinity of isolated liver microsomes for aniline, N-ethylaniline, oxygen, ethyl isocyanide and carbon monoxide by the treatment of young rabbits with phenobarbital].[用苯巴比妥处理幼兔对离体肝微粒体与苯胺、N-乙基苯胺、氧、乙基异氰化物和一氧化碳亲和力的影响]

Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):161-3.

3

The role of cytochrome P-450 in the N-oxidation of individual amines.细胞色素P-450在单个胺类N-氧化中的作用。

Drug Metab Dispos. 1973 Jan-Feb;1(1):299-313.

4

The binding of hexobarbital and aniline to cytochrome P-450 of liver microsomes from control and phenobarbital-treated rats of different ages.己巴比妥和苯胺与不同年龄的对照及苯巴比妥处理大鼠肝脏微粒体细胞色素P-450的结合。

Acta Biol Med Ger. 1976;35(5):627-33.

5

Omega- and (omega-1)-hydroxylation of 4-chloropropionanilide in liver microsomes of rabbits treated weith phenobarbital or 3-methylcholanthrene.在经苯巴比妥或3-甲基胆蒽处理的家兔肝脏微粒体中4-氯丙酰苯胺的ω-和（ω-1）-羟基化作用

Biochem Pharmacol. 1973 Oct 15;22(20):2575-80.

6

[Hydroxylation of progesterone by rabbit liver microsomes. Changes in metabolite pattern after phenobarbital treatment of the animals].

Naunyn Schmiedebergs Arch Pharmakol. 1970;267(3):265-77.

7

Species and substrate differences of liver microsomal N-dealkylation and N-oxidation of tertiary amines and N-dealkylation of N-oxides.肝脏微粒体中叔胺的N-脱烷基化和N-氧化以及N-氧化物的N-脱烷基化的物种和底物差异。

Xenobiotica. 1971 Jul-Oct;1(4):533-4. doi: 10.3109/00498257109041522.

8

Species differences in the induction of microsomal hemoproteins and 3,4-benzpyrene hydroxylase by phenobarbital and 3-methylcholanthrene.苯巴比妥和3-甲基胆蒽对微粒体血红蛋白和3,4-苯并芘羟化酶诱导作用的种属差异。

J Pharmacol Exp Ther. 1970 Oct;175(1):4-11.

9

Interaction of aromatic nitro compounds with reduced hepatic microsomal cytochrome P-450.

Drug Metab Dispos. 1975 Jul-Aug;3(4):266-74.

10

Effects of inducers of liver microsomal enzymes on the composition of microsomal hemoprotein.肝微粒体酶诱导剂对微粒体血红素蛋白组成的影响。

Adv Cytopharmacol. 1971 May;1:241-7.

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Drug metabolism and interaction with particular reference to the liver.药物代谢及相互作用，特别涉及肝脏。

Drugs. 1971;2(3):177-89. doi: 10.2165/00003495-197102030-00001.

2

Active centers of microsomal cytochrome P-450 determined with metyrapone by mutural depletion system kinetics.采用甲吡酮通过相互消耗系统动力学测定微粒体细胞色素P-450的活性中心。

Naunyn Schmiedebergs Arch Pharmacol. 1973;277(1):39-52. doi: 10.1007/BF00498783.

3

Effects of enzyme induction and inhibition on microsomal oxidation of 1,4-benzodiazepines.

Naunyn Schmiedebergs Arch Pharmacol. 1976 Jul;294(1):91-7. doi: 10.1007/BF00692789.