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The influence of some hepatic enzyme inducers and inhibitors on extrahepatic drug metabolism.

作者信息

Lake B G, Hopkins R, Chakraborty J, Bridges J W, Parke D V

出版信息

Drug Metab Dispos. 1973 Jan-Feb;1(1):342-9.

PMID:4149403
Abstract
摘要

相似文献

1
The influence of some hepatic enzyme inducers and inhibitors on extrahepatic drug metabolism.某些肝酶诱导剂和抑制剂对肝外药物代谢的影响。
Drug Metab Dispos. 1973 Jan-Feb;1(1):342-9.
2
Hepatic drug metabolism in pseudohermaphroditic rats.假两性畸形大鼠的肝脏药物代谢
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Effects of chronic administration of polybrominated biphenyls on parameters associated with hepatic drug metabolism.长期施用多溴联苯对与肝脏药物代谢相关参数的影响。
Res Commun Chem Pathol Pharmacol. 1976 Jan;13(1):75-82.
4
Some selected studies on hepatic microsomal drug-metabolizing enzymes--environment interactions.
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[Spectral properties of cytochrome P450 following induction with phenobarbital, benzopyrene and methylcholanthrene].[苯巴比妥、苯并芘和甲基胆蒽诱导后细胞色素P450的光谱特性]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):189-90.
6
Effects of inducers and inhibitors of cytochrome P-450-linked monooxygenases on the toxicity, in vitro metabolism and in vivo irreversible binding of 2-methylnaphthalene in mice.细胞色素P-450连接的单加氧酶诱导剂和抑制剂对小鼠体内2-甲基萘的毒性、体外代谢及体内不可逆结合的影响。
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Species differences in the induction of microsomal hemoproteins and 3,4-benzpyrene hydroxylase by phenobarbital and 3-methylcholanthrene.苯巴比妥和3-甲基胆蒽对微粒体血红蛋白和3,4-苯并芘羟化酶诱导作用的种属差异。
J Pharmacol Exp Ther. 1970 Oct;175(1):4-11.
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The induction of hepatic cytochrome P-450 in C57 BL/10 and DBA/2 mice by isosafrole and piperonyl butoxide. A comparative study with other inducing agents.异黄樟素和胡椒基丁醚对C57 BL/10和DBA/2小鼠肝细胞色素P-450的诱导作用。与其他诱导剂的比较研究。
Chem Biol Interact. 1980 Aug;31(2):189-201. doi: 10.1016/0009-2797(80)90005-8.
9
Inhibition by piperonyl butoxide of phenobarbital mediated induction of mouse liver microsomal enzyme activity.
Res Commun Chem Pathol Pharmacol. 1974 Jul;8(3):515-26.
10
Biliary excretion of 3-methylcholanthrene as controlled by its metabolism.
J Pharmacol Exp Ther. 1972 Nov;183(2):420-6.

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Effect of topically applied phenobarbital on O-dealkylase activity in mouse skin.局部应用苯巴比妥对小鼠皮肤O-脱烷基酶活性的影响。
Experientia. 1982 May 15;38(5):604-5. doi: 10.1007/BF02327074.
2
The renal cytochrome P-450 arachidonic acid system.肾脏细胞色素P-450花生四烯酸系统。
Pediatr Nephrol. 1992 Sep;6(5):490-8. doi: 10.1007/BF00874022.
3
Differential effects of antioxidants, steroids and other compounds on benzo(a)pyrene 3-hydroxylase activity in various tissues of rat.抗氧化剂、类固醇及其他化合物对大鼠不同组织中苯并(a)芘3-羟化酶活性的差异影响。
Br J Cancer. 1979 Jul;40(1):105-12. doi: 10.1038/bjc.1979.146.
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Aldrin epoxidase in liver and small intestine of rat and Japanese quail.大鼠和日本鹌鹑肝脏及小肠中的艾氏剂环氧化酶
Bull Environ Contam Toxicol. 1979 Mar;21(4-5):498-501. doi: 10.1007/BF01685460.