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[嗅觉-生殖综合征（作者译）]

[The olfactor-genital syndrome (author's transl)].

作者信息

Rjosk H K, Goebel R

出版信息

Geburtshilfe Frauenheilkd. 1978 Jan;38(1):25-9.

PMID:414956
Abstract
  1. Only FSH was increased after intravenous administration of 0.025 mg of GnRH in 2 female patients suffering from olfacto-genital syndrome. LH-serum-concentrations increased significantly, only when 0.1 mg GnRH was applicated intravenously twice with an interval of one hour.2. The response of hPRL-secretion to 0.2 mg TRH was found normal in both patients. However, when 25 mg chlorpromacine were administered intramuscularly, only one patient responded with an adequate rise of serum-hPRL. 3. One patient became pregnant during treatment with HMG/HCG. The clinical course of pregnancy was quite normal. HPL- and HCG-levels were in the normal, hPRL in the low normal range during pregnancy.
摘要

  1. 在2例患有嗅觉生殖器综合征的女性患者中，静脉注射0.025毫克促性腺激素释放激素（GnRH）后，仅卵泡刺激素（FSH）升高。仅当静脉注射0.1毫克GnRH，间隔1小时，注射两次时，血清促黄体生成素（LH）浓度才显著升高。

  2. 发现两名患者对0.2毫克促甲状腺激素释放激素（TRH）的人催乳素（hPRL）分泌反应正常。然而，当肌肉注射25毫克氯丙嗪时，只有一名患者血清hPRL有足够升高的反应。

  3. 一名患者在接受人绝经期促性腺激素/人绒毛膜促性腺激素（HMG/HCG）治疗期间怀孕。妊娠临床过程相当正常。妊娠期间，人胎盘催乳素（HPL）和人绒毛膜促性腺激素（HCG）水平正常，hPRL处于低正常范围。

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1
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Geburtshilfe Frauenheilkd. 1978 Jan;38(1):25-9.
2
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[Variations of the plasma levels of gonadotrophins (FSH and LH) and of its response to stimulation with gonadotrophin releasing hormone (GnRH) with different plasma levels of prolactin (PRL) in women with the syndrome of galactorrhea-amenorrhea (author's transl)].[溢乳-闭经综合征女性中不同催乳素（PRL）血浆水平下促性腺激素（FSH和LH）的血浆水平变化及其对促性腺激素释放激素（GnRH）刺激的反应（作者译）]
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