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On the interaction of drugs with the cholinergic nervous system. II. Cross-tolerance between phencyclidine derivatives and cholinergic drugs.

作者信息

Pinchasi I, Maayani S, Egozi Y, Sokolovsky M

出版信息

Psychopharmacology (Berl). 1978 Jan 31;56(1):37-40. doi: 10.1007/BF00571405.

DOI:10.1007/BF00571405
PMID:415324
Abstract

A symmetrical cross-tolerance was found between two phencyclidine derivatives--phencyclidine and cyclohexamine--and also between two cholinergic drugs--physostigmine and oxotremorine. On the other hand, mice rendered tolerant to the phencyclidine derivatives showed cross-tolerance to these cholinergic drugs, but no cross-tolerance was observed in the opposite direction. The applicability of such experiments to the elucidation of neurochemical interactions of centrally acting drugs is discussed.

摘要

相似文献

1
On the interaction of drugs with the cholinergic nervous system. II. Cross-tolerance between phencyclidine derivatives and cholinergic drugs.
Psychopharmacology (Berl). 1978 Jan 31;56(1):37-40. doi: 10.1007/BF00571405.
2
On the interaction of drugs with the cholinergic nervous system--III. Tolerance to phencyclidine derivatives: in vivo and in vitro studies.论药物与胆碱能神经系统的相互作用——III. 对苯环利定衍生物的耐受性：体内和体外研究
Biochem Pharmacol. 1977 Sep 15;26(18):1671-9. doi: 10.1016/0006-2952(77)90144-7.
3
On the interaction of drugs with the cholinergic nervous system. I. Tolerance to phencyclidine derivatives in mice: pharmacological characterization.
Psychopharmacology (Berl). 1978 Jan 31;56(1):27-36. doi: 10.1007/BF00571404.
4
Some structure activity relationships of phencyclidine derivatives as anticholinergic agents in vitro and in vivo.苯环利定衍生物作为抗胆碱能药物在体内外的一些构效关系。
Prog Clin Biol Res. 1979;27:91-106.
5
Interaction of phencyclidine with drugs affecting cholinergic neurotransmission.苯环利定与影响胆碱能神经传递的药物之间的相互作用。
Neuropharmacology. 1980 Feb;19(2):151-3. doi: 10.1016/0028-3908(80)90130-6.
6
On the interaction of drugs with the cholinergic nervous system--IV. Tolerance to oxotremorine in mice: in vivo and in vitro studies.关于药物与胆碱能神经系统的相互作用——IV. 小鼠对氧化震颤素的耐受性：体内和体外研究
Biochem Pharmacol. 1977 Sep 15;26(18):1681-7. doi: 10.1016/0006-2952(77)90145-9.
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Influence of cholinergic modifiers on phencyclidine-induced acute toxicity.胆碱能调节剂对苯环利定诱导的急性毒性的影响。
Pharmacol Res Commun. 1983 Mar;15(3):291-305. doi: 10.1016/s0031-6989(83)80014-9.
8
On the interaction of drugs with the cholinergic nervous system--V. Characterization of some effects induced by physostigmine in mice: in vivo and in vitro studies.药物与胆碱能神经系统的相互作用——Ⅴ. 毒扁豆碱对小鼠诱导的某些效应的特征：体内和体外研究
Biochem Pharmacol. 1978 Jan 15;27(2):203-11. doi: 10.1016/0006-2952(78)90302-7.
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Phencyclidine (PCP) and derivatives: pharmacology and structure-activity relationships [proceedings].苯环利定（PCP）及其衍生物：药理学与构效关系[会议论文集]
Psychopharmacol Bull. 1980 Oct;16(4):57-9.
10
Interactions between phencyclidine and cholinergic excitation of hippocampal pyramidal neurons.苯环利定与海马锥体神经元胆碱能兴奋之间的相互作用。
Neuropharmacology. 1982 Aug;21(8):729-32. doi: 10.1016/0028-3908(82)90056-9.

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本文引用的文献

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OBSERVATIONS ON DIRECT AND CROSS TOLERANCE WITH LSD AND D-AMPHETAMINE IN MAN.人体中 LSD 与右旋苯丙胺的直接耐受性和交叉耐受性观察
Psychopharmacologia. 1963 Oct 24;5:1-15. doi: 10.1007/BF00405570.
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Cross tolerance between LSD and psilocybin.麦角酸二乙酰胺（LSD）和裸盖菇素之间的交叉耐受性。
急性和慢性给予苯环己哌啶对大鼠前脑3H-色氨酸向3H-5-羟色胺转化的影响。
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Psychopharmacology (Berl). 1982;78(2):116-20. doi: 10.1007/BF00432246.
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Behavioral effects of chronic phencyclidine administration in rats.长期给予大鼠苯环利定的行为学效应
Psychopharmacology (Berl). 1982;76(1):52-6. doi: 10.1007/BF00430755.
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Effects of phencyclidine on active avoidance and escape in rats.苯环利定对大鼠主动回避和逃避行为的影响。
Psychopharmacology (Berl). 1985;86(1-2):237-40. doi: 10.1007/BF00431717.
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On the interaction of drugs with the cholinergic nervous system. I. Tolerance to phencyclidine derivatives in mice: pharmacological characterization.
Psychopharmacology (Berl). 1978 Jan 31;56(1):27-36. doi: 10.1007/BF00571404.
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On the interaction of drugs with the cholinergic nervous system. VI. Tolerance to physostigmine in mice.论药物与胆碱能神经系统的相互作用。VI. 小鼠对毒扁豆碱的耐受性
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The effects of some hallucinogenic drugs upon the metabolism of noradrenaline.某些致幻药物对去甲肾上腺素代谢的影响。
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Life Sci. 1969 Aug 1;8(15):805-14. doi: 10.1016/0024-3205(69)90141-6.
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Tolerance and cross-tolerance among psychotomimetic drugs.拟精神病药物之间的耐受性和交叉耐受性。
Psychopharmacologia. 1968 Sep 20;13(3):267-74. doi: 10.1007/BF00401404.
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Some effects of an hallucinogenic drug (phencyclidine) on neurohumoral substances.一种致幻药物（苯环利定）对神经体液物质的某些影响。
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Psychotropic drug influences on brain acetylcholine utilization.精神药物对脑乙酰胆碱利用的影响。
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Interaction of phencyclidine with drugs affecting noradrenaline metabolism in the rat brain.苯环利定与影响大鼠脑内去甲肾上腺素代谢的药物之间的相互作用。
Psychopharmacologia. 1972;23(1):86-90. doi: 10.1007/BF00414416.