Kleinberger G, Gabl F, Gassner A, Lochs H, Pall H, Pichler M
Wien Klin Wochenschr. 1978 Mar 3;90(5):169-72.
Hypophosphatemia is a much commoner condition than generally recognized from investigations on this subject so far. Hypophosphatemia may cause ill-defined disturbances in the course of illness in patients with renal insufficiency. On the basis of our results we recommend the addition of 5--10 mmol phosphate (155--310 mg phosphorus) per 1000 kcal. of the nutrient solution right from the start of parenteral nutrition in patients with chronic renal insufficiency. The phosphate dosage must be further increased, at least temporarily, in hypophosphatemic patients with acute renal insufficiency. Serum phosphate determination should be obligatory in patients with renal insufficiency at the time when the patient is first seen. It should also be performed at least every second day during the first week of parenteral nutrition. Thereafter, the determination of serum phosphate twice weekly should suffice to control the dosage of phosphate required by the patient.
低磷血症是一种比迄今为止关于该主题的研究所普遍认识到的更为常见的病症。低磷血症可能在肾功能不全患者的病程中引起不明确的紊乱。根据我们的研究结果，我们建议在慢性肾功能不全患者开始肠外营养时，每1000千卡营养液中添加5 - 10毫摩尔磷酸盐（155 - 310毫克磷）。对于急性肾功能不全的低磷血症患者，磷酸盐剂量必须进一步增加，至少是暂时增加。对于初次就诊时患有肾功能不全的患者，血清磷酸盐测定应成为常规检查。在肠外营养的第一周，也应至少每两天进行一次血清磷酸盐测定。此后，每周测定两次血清磷酸盐就足以控制患者所需的磷酸盐剂量。
