Wagner H, Wirth W
Z Rheumatol. 1978 Jan-Feb;37(1-2):4-11.
In basic therapy of Rheumatoid Arthritis gold is preferred. Continued as well as discontinued therapy is used. The effect of gold is of complex nature. Gold is localized in cells of the RES and mesenchyme main in the inflammatory area. The passing acceleration of mesenchyme metabolism possibly shortens the duration of the inflammatory process. Gold further shows effects on cellular and subcellular membranes, on collagen, ACTH-production and on immune reactions. Patients with high activity and slow progression of their disease are especially suitable for chrysotherapy. Low maintenance of gold levels is effective and inhibits toxic-allergical reactions may be in a sort of desensitisation.