金属作为诱变剂。

Metals as mutagens.

作者信息

Flessel C P

出版信息

Adv Exp Med Biol. 1977;91:117-28. doi: 10.1007/978-1-4684-0796-9_9.

Abstract

A number of metals are mutagenic in bacteria or phage. These include compounds of arsenic, chromium, copper, iron, manganese, molybdenum, platinum, and selenium. Compounds containing alumium, antimony, arsenic, cadmium, copper, lead, mercury, nickel, and tellium have been shown to induce chromosomal aberrations or abnormal cell divisions in animal or plant cells. Genetic evidence suggests that arsenic, chromium, and molybdenum compounds may influence the accuracy of DNA repair processes in microorganisms.

摘要

许多金属在细菌或噬菌体中具有致突变性。这些金属包括砷、铬、铜、铁、锰、钼、铂和硒的化合物。已表明含有铝、锑、砷、镉、铜、铅、汞、镍和碲的化合物会在动物或植物细胞中诱导染色体畸变或异常细胞分裂。遗传学证据表明，砷、铬和钼的化合物可能会影响微生物中DNA修复过程的准确性。