Olatunde A
Afr J Med Med Sci. 1977 Mar;6(1):27-32.
Attention has once again been directed to the very uncomfortable itching following chloroquine chemotherapy of malaria in about 8% of the Nigeria population. Six typical case reports are presented. We have been able to identify three stages in the course of the itching and in the second stage, four phases have been outlined. The major implications of the pruritus are briefly discussed in respect to its effect on malaria treatment. Its possible link with more serious adverse effects and variations in drug metabolism are also mentioned. The treatment outlined is directed towards minimizing the intensity and duration of the itching reaction.
人们的注意力再次转向尼日利亚约8%的人口在接受疟疾氯喹化疗后出现的非常不适的瘙痒。本文呈现了六例典型病例报告。我们已经能够确定瘙痒过程中的三个阶段，并且在第二阶段，概述了四个时期。本文简要讨论了瘙痒症对疟疾治疗的影响方面的主要问题。还提到了它与更严重不良反应以及药物代谢差异的可能联系。所概述的治疗方法旨在将瘙痒反应的强度和持续时间降至最低。
