Young G A, Hill G L
Am J Clin Nutr. 1978 Mar;31(3):429-35. doi: 10.1093/ajcn/31.3.429.
Six plasma proteins, two anthropometric measurements, hemoglobin and total lymphocytes were determined in 54 surgical patients and 19 normal individuals. Preoperative patients had a low mean values for prealbumin, retinol binding protein, and arm muscle circumference. In postoperative patients, plasma transferrin, albumin, hemoglobin, total lymphocytes and body weight were also low and complement C3 was higher than normal. A correlation matrix for 10 variables showed interrelationships between the biochemical and anthropometric data. Prealbumin and transferrin were highly correlated with most of the variables. The effects of protein-calorie malnutrition were analyzed from the data ranked and grouped according to the plasma prealbumin or transferrin concentration. Those groups with low mean values for these proteins also had low values for most of the other variables. Protein calorie malnutrition in surgical patients may be conveniently assessed from plasma prealbumin, transferrin, arm muscle circumference, percentage weight loss, and hemoglobin.
对54例外科手术患者和19名正常个体测定了六种血浆蛋白、两项人体测量指标、血红蛋白和总淋巴细胞数。术前患者的前白蛋白、视黄醇结合蛋白和上臂肌肉周长平均值较低。术后患者的血浆转铁蛋白、白蛋白、血红蛋白、总淋巴细胞数和体重也较低，补体C3高于正常水平。一个包含10个变量的相关矩阵显示了生化数据和人体测量数据之间的相互关系。前白蛋白和转铁蛋白与大多数变量高度相关。根据血浆前白蛋白或转铁蛋白浓度对数据进行排序和分组，分析蛋白质-热量营养不良的影响。这些蛋白质平均值较低的组，大多数其他变量的值也较低。外科手术患者的蛋白质热量营养不良可以通过血浆前白蛋白、转铁蛋白、上臂肌肉周长、体重减轻百分比和血红蛋白方便地进行评估。
