Hoyt C S, Billson F A
Br J Ophthalmol. 1978 Jan;62(1):3-6. doi: 10.1136/bjo.62.1.3.
Seven patients with optic nerve hypoplasia, born of epileptic mothers, are presented. All the mothers took anticonvulsants during pregnancy. The possibility that maternal anticonvulsant therapy may play a role in the genesis of optic nerve hypoplasia is discussed in the light of what is known about the teratogenicity of these agents.
本文报告了7例视神经发育不全的患儿,他们的母亲均患有癫痫。所有母亲在孕期都服用了抗惊厥药物。鉴于已知这些药物的致畸性,本文讨论了母亲抗惊厥治疗可能在视神经发育不全的发生中所起的作用。