Sifri M, Lowry D C, Kratzer F H, Norris L C
J Nutr. 1978 Apr;108(4):719-30. doi: 10.1093/jn/108.4.719.
Five experiments were conducted in which various levels of nitrilotriacetic acid (NTA or its salt, Na2NTA) disodium ethylenediaminetetraacetic acid (Na2EDTA) and calcium (Ca) were fed to young chicks, young quail and adult quail. The duration of trials was from 1 to 28 days of age for chicks, 7 to 49 for young quail and 167 to 210 for adult quail. Feeding 0.71% NTA or an equimolar level of Na2NTA caused a moderate decrease in chicks weight and Na2EDTA caused a drastic decrease in body weight of chicks and adult quail. Feeding Na2EDTA caused greater mortality in chicks receiving a low Ca diet than a higher level of Ca. Plasma Ca levels were significantly increased by NTA in young quail and by Na2NTA in adult quail, in contrast, they were significantly decreased by Na2EDTA in adult quail. Dietary NTA promoted greater tibia mineralization (ash/dry matter) in growing chicks. Dietary NTA increased the deposition of zinc (Zn) and manganese (Mn) in the chicks tibia, but, it decreased magnesium (Mg). On the other hand, Na2EDTA caused a significant decrease in Zn and Fe in the chicks tibia and a significant increase in Mn. Coturnix are less sensitive than chickens in responding to dietary chelates.
进行了五项实验，分别给幼雏鸡、幼鹌鹑和成年鹌鹑投喂不同水平的次氮基三乙酸（NTA或其盐，Na₂NTA）、乙二胺四乙酸二钠（Na₂EDTA）和钙（Ca）。雏鸡的试验期为1至28日龄，幼鹌鹑为7至49日龄，成年鹌鹑为167至210日龄。投喂0.71%的NTA或等摩尔水平的Na₂NTA会使雏鸡体重适度下降，而Na₂EDTA会使雏鸡和成年鹌鹑的体重急剧下降。在低钙饮食的雏鸡中，投喂Na₂EDTA导致的死亡率高于高钙饮食的雏鸡。NTA使幼鹌鹑的血浆钙水平显著升高，Na₂NTA使成年鹌鹑的血浆钙水平显著升高，相反，Na₂EDTA使成年鹌鹑的血浆钙水平显著降低。日粮中的NTA促进了生长中的雏鸡胫骨矿化（灰分/干物质）。日粮中的NTA增加了雏鸡胫骨中锌（Zn）和锰（Mn）的沉积，但降低了镁（Mg）的含量。另一方面，Na₂EDTA使雏鸡胫骨中的锌和铁显著减少，锰显著增加。鹌鹑对日粮螯合物的反应比鸡更不敏感。
