人类免疫球蛋白G和M共有的抗原决定簇：构象抗原的重要性。
Antigenic determinants common to human immunoglobulins G and M: importance of conformational antigens.
作者信息
Seligmann M, Mihaesco C, Meshaka G
出版信息
Science. 1966 Nov 11;154(3750):790-1. doi: 10.1126/science.154.3750.790.
PMID:4162133
Abstract
Antiserums produced against certain isolated human myeloma IgGglobulins and absorbed in order to show only individual antigenic specificity crossreact with certain Waldenstrom IgM-globulins. Some of the common antigenic determinants revealed by these cross-reactions depend on the tertiary and quaternary structure of the IgG and IgM molecules and are independent of their K and L light-chain antigenic types.
摘要
针对某些分离出的人骨髓瘤IgG球蛋白制备并经过吸收处理以仅显示个体抗原特异性的抗血清，与某些瓦尔登斯特伦巨球蛋白血症的IgM球蛋白发生交叉反应。这些交叉反应所揭示的一些共同抗原决定簇取决于IgG和IgM分子的三级和四级结构，且与其K和L轻链抗原类型无关。
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