Induction of hepatic 7,12-dimethylbenz(alpha)anthracene metabolism by polycyclic aromatic hydrocarbons and aromatic azo derivatives.
作者信息
Conney A H, Levin W
出版信息
Life Sci. 1966 Mar;5(5):465-71. doi: 10.1016/0024-3205(66)90163-9.
PMID:4164142
Abstract
摘要
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Induction of hepatic 7,12-dimethylbenz(alpha)anthracene metabolism by polycyclic aromatic hydrocarbons and aromatic azo derivatives.多环芳烃和芳香偶氮衍生物对肝脏7,12-二甲基苯并(α)蒽代谢的诱导作用。
Life Sci. 1966 Mar;5(5):465-71. doi: 10.1016/0024-3205(66)90163-9.
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Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation of benz( )anthracene 8,9-oxide and 10,11-dihydrobenz( )anthracene 8,9-oxide and their metabolism by rat liver preparations.芳香多环烃的环氧衍生物。苯并（ ）蒽8,9 - 氧化物和10,11 - 二氢苯并（ ）蒽8,9 - 氧化物的制备及其在大鼠肝脏制剂中的代谢。
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Synthesis of metabolites of 7,12-dimethylbenz[a]anthracene. 4-Hydroxy-7,12-dimethylbenz[a]anthracene, 7-hydroxymethyl-12-methylbenz[a]anthracene, their methyl ethers, and acetoxy derivatives.
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AROMATIC AZO DERIVATIVES PREVENTING MAMMARY CANCER AND ADRENAL INJURY FROM 7,12-DIMETHYLBENZ(A)ANTHRACENE.预防7,12-二甲基苯并(a)蒽所致乳腺癌和肾上腺损伤的芳香族偶氮衍生物
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In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons.多环烃K区域衍生物对啮齿动物细胞的体外转化
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The effect of pretreatment with adrenal-protecting compounds on the metabolism of 7,12-dimethylbenz[a]anthracene and related compounds by rat-liver homogenates.肾上腺保护化合物预处理对大鼠肝脏匀浆代谢7,12-二甲基苯并[a]蒽及相关化合物的影响。
Biochem J. 1967 Aug;104(2):394-403. doi: 10.1042/bj1040394.
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Metabolic pathways of 7,12-dimethylbenz[a]anthracene in hepatic microsomes.7,12-二甲基苯并[a]蒽在肝微粒体中的代谢途径。
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2601-5. doi: 10.1073/pnas.72.7.2601.
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