Nordborg C
Acta Neuropathol. 1978 Feb 20;41(2):103-8. doi: 10.1007/BF00689760.
The current investigation comprised normal young rats as well as rats submitted to a 50% food reduction or severe protein restriction. Isolated nerve fibres from lumbar spinal roots and sciatic nerves were investigated with reference to the relation between length and diameter of internodes as well as variation of internodal length along single nerve fibres. The present results do not support the view that protein-calorie malnutrition should cause neuropathy. Internodal segments were, on an average, shorter in relation to their thickness in young rats submitted to severe protein restriction or a 50% food reduction. The deviation was most marked in low-protein animals and particularly among coarser internodal segments. An inhibition of longitudinal growth was considered to be the main factor behind the difference between malnourished and normal rats.
当前的研究包括正常的幼年大鼠以及经历了50%食物减少或严重蛋白质限制的大鼠。对来自腰脊髓神经根和坐骨神经的孤立神经纤维进行了研究，以探讨节间长度与直径之间的关系以及沿单根神经纤维节间长度的变化。目前的结果不支持蛋白质-热量营养不良会导致神经病变的观点。在经历严重蛋白质限制或50%食物减少的幼年大鼠中，节间段相对于其厚度平均较短。这种偏差在低蛋白动物中最为明显，尤其是在较粗的节间段中。纵向生长的抑制被认为是营养不良大鼠与正常大鼠之间差异的主要因素。
