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非洲人的中风

Stroke in the Africans.

作者信息

Osuntokun B O

出版信息

Afr J Med Med Sci. 1977 Jun;6(2):39-53.

PMID:416666
Abstract

Stroke is increasingly becoming a major cause of death and morbidity in African population among most of which the frequencies of hypertension are considerable, although hard data based on community surveys are lacking and most of the information available is from hospital data. The epidemiology of stroke in the Africans is reviewed. The frequencies in hospital populations varied from 0.9% to 4.0% and stroke accounted for 0.5% to 45% of neurological admissions. There is male predominance in published series. The main risk factors are hypertension, diabetes mellitus and homozygous sickle cell disease (in children only). Ischaemic stroke is by far the commonest clinical type encountered. These conclusions are further supported by experience at Ibadan, of over 1100 Africans seen over 18 years reported briefly in this communication. The results of the first community study over a 2-year period on the incidence of stroke in an African Urban (Ibadan) Community are presented. The study was carried out as part of a multinational multicentric study initiated and sponsored by the World Health Organization. The male to female ratio was five to two. Incidence rates reached peaks in the eighth decade in males and in seventh decade in females and were higher in males in all age groups, and the rates are comparable with those recorded in European populations, except in those under the age of 40 in Ibadan, in which age-specific incidence rates are considerably lower than in European and Japanese populations. Hypertension, diabetes mellitus constituted the main risk factors. Mortality and recurrence rates are described and are similar to experience in the Caucasians. Hypertension in the Nigerians predispose to a high frequency of cerebrovascular disease other than through mainly cerebral atherosclerosis. With increasing longevity of Nigerians and other Africans, the mortality and morbidity caused by cerebrovascular disease would probably become of enormous dimensions and adequate control of high blood pressure on a community basis may be the only way of preventing this: this would be desirable as myocardial infarction in contradistinction to hypertensive heart disease is an uncommon complication of high blood pressure in the Africans and prevention of hypertensive heart disease as shown by experience elsewhere can be achieved by control of high blood pressure, which does not seem to prevent ischaemic myocardial disease.

摘要

中风日益成为非洲人群死亡和发病的主要原因,在大多数非洲人中,高血压的发病率相当高,尽管缺乏基于社区调查的确切数据,且现有大部分信息来自医院数据。本文对非洲人的中风流行病学进行了综述。医院人群中的发病率从0.9%到4.0%不等,中风占神经科住院人数的0.5%到45%。在已发表的系列研究中男性占主导。主要风险因素为高血压、糖尿病和纯合子镰状细胞病(仅在儿童中)。缺血性中风是迄今为止最常见的临床类型。伊巴丹18年来诊治的1100多名非洲人的经验进一步支持了这些结论,本文对此进行了简要报道。本文介绍了在一个非洲城市(伊巴丹)社区进行的为期两年的中风发病率首次社区研究结果。该研究是由世界卫生组织发起和赞助的一项多国多中心研究的一部分。男女比例为5比2。发病率在男性的第八个十年和女性的第七个十年达到峰值,各年龄组男性发病率均高于女性,且该发病率与欧洲人群记录的发病率相当,但伊巴丹40岁以下人群除外,该年龄段的年龄特异性发病率远低于欧洲和日本人群。高血压、糖尿病是主要风险因素。本文描述了死亡率和复发率,其与白种人的情况相似。尼日利亚人的高血压除主要通过脑动脉粥样硬化外,还易导致脑血管疾病高发。随着尼日利亚人和其他非洲人寿命的延长,脑血管疾病导致的死亡率和发病率可能会大幅上升,在社区层面充分控制高血压可能是预防这种情况的唯一途径:这是可取的,因为与高血压性心脏病不同,心肌梗死在非洲人中是高血压的罕见并发症,而且正如其他地方的经验所示,通过控制高血压可以预防高血压性心脏病,但这似乎无法预防缺血性心肌病。

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