Ellis J M, Lee S I
Epilepsia. 1978 Apr;19(2):119-28. doi: 10.1111/j.1528-1157.1978.tb05021.x.
Six patients ranging in age from 42 to 69 with no prior history of seizure disorder presented an acute prolonged or intermittent confusional state, with or without psychotic symptoms, as an ictal manifestation. The EEGs demonstrated protracted generalized spike and wave discharges, but full diagnostic evaluation disclosed no evident cause for the seizures. All promptly responded to small amounts of intravenous diazepam and subsequent oral phenytoin and phenobarbital. Three of the six patients had focal spike or sharp wave discharges on EEGs recorded subsequently, suggesting that the episodes may reflect secondary generalized seizures in some cases. These cases do not fit in the classic category of petit mal status and appear to be a distinct entity.
6例年龄在42岁至69岁之间、既往无癫痫发作病史的患者，出现急性持续性或间歇性意识模糊状态，伴有或不伴有精神病性症状，作为发作期表现。脑电图显示持续性广泛性棘波和慢波放电，但全面的诊断评估未发现癫痫发作的明显病因。所有患者均迅速对小剂量静脉注射地西泮以及随后口服苯妥英钠和苯巴比妥产生反应。6例患者中有3例在随后记录的脑电图上出现局灶性棘波或尖波放电，提示在某些情况下这些发作可能反映继发性全身性癫痫发作。这些病例不符合典型的小发作持续状态，似乎是一种独特的病症。
