双胞胎的血浆免疫球蛋白浓度。
Plasma immunoglobulin concentrations in twins.
作者信息
Rowe D S, Boyle J A, Buchanan W W
出版信息
Clin Exp Immunol. 1968 Mar;3(3):233-44.
Abstract
A study has been made of the similarity of concentrations of IgG, IgA and IgM in twins. The results provide evidence for the genetic control of all three immunoglobulins in adolescence, but in adults genetic control was demonstrable only for IgG in males. The findings suggest that although genetic factors regulating all classes of immunoglobulin levels in adults cannot be excluded by this study, if such factors do exist their effects are relatively small or are confined to certain individuals. This conclusion suggests that immunoglobulin concentrations in healthy adults will not form useful indices of future susceptibility to genetically determined diseases of immunity.
摘要
一项关于双胞胎中IgG、IgA和IgM浓度相似性的研究已经展开。研究结果为青春期所有三种免疫球蛋白的遗传控制提供了证据，但在成年人中，仅在男性中可证明IgG存在遗传控制。研究结果表明，虽然本研究不能排除调节成年人所有免疫球蛋白水平的遗传因素，但如果确实存在此类因素，其影响相对较小或仅限于某些个体。这一结论表明，健康成年人的免疫球蛋白浓度不会成为未来对遗传性免疫疾病易感性的有用指标。
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