Kalff M W, Hijmans W
Clin Exp Immunol. 1969 Nov;5(5):469-77.
Serum levels of the immunoglobulins IgG, IgA and IgM were determined by single radial immunodiffusion in twin material consisting of eighty-nine monozygotic and forty-two dizygotic twin pairs. Analysis of variance was performed on the quantitative results; there is strong evidence for both genetic and environmental influences on the serum levels of the three immunoglobulins; a genetic influence is apparent in both males and females, but an environmental influence could only be analysed without the distinction according to sex, because the subgroups were too small for separate analysis. The results are discussed and compared with data from the literature.
采用单向辐射免疫扩散法,在由89对单卵双胞胎和42对双卵双胞胎组成的双胞胎样本中测定血清免疫球蛋白IgG、IgA和IgM的水平。对定量结果进行方差分析;有充分证据表明基因和环境因素均会影响这三种免疫球蛋白的血清水平;基因影响在男性和女性中均很明显,但环境影响只能在不区分性别的情况下进行分析,因为亚组样本量太小,无法进行单独分析。对结果进行了讨论,并与文献数据进行了比较。