Levy B M, Nelms D C, Dreizen S, Bernick S
Primates Med. 1978;10:205-14.
The histologic reaction of the marmoset periodontium to a single intragingival injection of CFA was followed sequentially over a 2-week period. The earliest lesions were nonspecific and similar to IFA-induced responses. After 4 days the CFA-produced lesions were markedly destructive of periodontal bone, whereas the IFA reaction was not, indicating that the alveolar bone destruction that stemmed form the CFA injection may have been immunologically mediated.
在2周的时间内，对狨猴牙周组织对单次龈内注射弗氏完全佐剂（CFA）的组织学反应进行了连续观察。最早的病变是非特异性的，类似于弗氏不完全佐剂（IFA）诱导的反应。4天后，CFA产生的病变对牙周骨具有明显的破坏作用，而IFA反应则没有，这表明由CFA注射引起的牙槽骨破坏可能是由免疫介导的。
