Shin H S, Snyderman R, Friedman E, Mellors A, Mayer M M
Science. 1968 Oct 18;162(3851):361-3. doi: 10.1126/science.162.3851.361.
The fifth component of guinea pig complement, with a sedimentation coefficient 7.8S, is cleaved by sensitized sheep erythrocytes treated with the first four components of complement into two fragments with sedimentation coefficients of 7.4S and 1.5S. The smaller fragment, with a molecular weight of about 15,000, possesses chemotactic activity for rabbit polymorphonuclear leukocytes, as well as anaphylatoxic activity for guinea pig ileum.
豚鼠补体的第五成分，沉降系数为7.8S，被用补体前四种成分处理过的致敏绵羊红细胞裂解为沉降系数分别为7.4S和1.5S的两个片段。较小的片段分子量约为15,000，对兔多形核白细胞具有趋化活性，对豚鼠回肠具有过敏毒素活性。
