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嗜酸性粒细胞的选择性趋化作用以及过敏反应嗜酸性粒细胞趋化因子(ECF-A)与补体第五成分(C5a)裂解片段之间的协同作用。

Selective attraction of eosinophils and synergism between eosinophil chemotactic factor of anaphylaxis (ECF-A) and a fragment cleaved from the fifth component of complement (C5a).

作者信息

Kay A B, Shin H S, Austen K F

出版信息

Immunology. 1973 Jun;24(6):969-76.

Abstract

ECF-A and C5a were chemotactic both for eosinophils and neutrophils. However, when eosinophils comprised approximately 10 per cent or more of a mixed leucocyte population, they were preferentially attracted by both of these agents. Marked synergism was observed between ECF-A and C5a in their ability to attract eosinophil leucocytes.

摘要

嗜酸性粒细胞趋化因子A(ECF-A)和C5a对嗜酸性粒细胞和中性粒细胞均有趋化作用。然而,当嗜酸性粒细胞在混合白细胞群体中占约10%或更多时,它们会优先被这两种因子吸引。在吸引嗜酸性粒细胞方面,观察到ECF-A和C5a之间在趋化能力上有明显的协同作用。

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