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苯乙胺对恒河猴的影响。

The effects of phenylethylamine in rhesus monkeys.

作者信息

Tinklenberg J R, Gillin J C, Murphy G M, Staub R, Wyatt R J

出版信息

Am J Psychiatry. 1978 May;135(5):576-8. doi: 10.1176/ajp.135.5.576.

Abstract

In controlled experiments rhesus monkeys that had received phenylethylamine (PEA) demonstrated behavior similar to that reported after the administration of amphetamines, except that tolerance to PEA did not develop. These findings are of psychiatric interest because PEA is found in the human body and is a specific substrate for type B MAO, which is found in decreased quantities in certain schizophrenic patients.

摘要

在对照实验中,接受苯乙胺(PEA)的恒河猴表现出与服用安非他明后所报告的行为相似,只是对PEA没有产生耐受性。这些发现具有精神病学方面的意义,因为PEA存在于人体中,并且是B型单胺氧化酶的特定底物,而在某些精神分裂症患者体内,这种酶的含量会减少。

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