单胺氧化酶抑制剂可增强恒河猴体内苯乙胺的作用。
Monoamine oxidase inhibitors potentiate phenylethylamine effects in rhesus monkeys.
作者信息
Staub R A, Gillin J C, Wyatt R J
出版信息
Biol Psychiatry. 1980 Jun;15(3):429-36.
PMID:6769508
Abstract
Acute pretreatment with either a Type A monoamine oxidase inhibitor (MAOI), clorgyline, or a Type B MAOI, pargyline, markedly reduced the dose of phenylethylamine (PEA) required to produce checking and a variety of other behavioral changes in rhesus monkeys. Doses of PEA (5 or 10 mg/kg) which previously were without effect, now produced significant behavioral changes in pretreatment animals.
摘要
用A型单胺氧化酶抑制剂（MAOI）氯吉兰或B型MAOI帕吉林进行急性预处理，可显著降低在恒河猴身上产生僵住反应及多种其他行为变化所需的苯乙胺（PEA）剂量。以前无效的PEA剂量（5或10毫克/千克），现在在预处理过的动物身上产生了显著的行为变化。
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