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卡波西肉瘤的放射治疗。

Radiotherapy of Kaposi's sarcoma.

作者信息

Holecek M J, Harwood A R

出版信息

Cancer. 1978 May;41(5):1733-8. doi: 10.1002/1097-0142(197805)41:5<1733::aid-cncr2820410513>3.0.co;2-s.

Abstract

Between 1958 and 1976, 34 patients with Kaposi's sarcoma were seen. Two patients were kidney transplant recipients. Co-existing malignancies were seen in 22% of patients. From 1958 to 1965, cutaneous lesions were treated solely with local radiotherapy techniques, single doses of 800 rads being found adequate to produce a complete response. In 1965, because of the multicentric occurrence of the disease and frequent recurrences after local radiotherapy techniques, extended field radiotherapy was begun. Ten of twelve patients thus treated responded completely. It is concluded that extended field radiotherapy using a single dose of 800 rads offers complete relief of symptoms and better control of the disease when compared to local radiotherapy. There was very little morbidity, with the extended field technique.

摘要

1958年至1976年间,共诊治了34例卡波西肉瘤患者。其中2例为肾移植受者。22%的患者同时存在其他恶性肿瘤。1958年至1965年期间,皮肤病变仅采用局部放射治疗技术,发现单次剂量800拉德足以产生完全缓解。1965年,由于该病多中心发病且局部放射治疗技术后频繁复发,开始采用扩大野放射治疗。接受该治疗的12例患者中有10例完全缓解。结论是,与局部放射治疗相比,单次剂量800拉德的扩大野放射治疗能完全缓解症状并更好地控制疾病。采用扩大野技术时,发病率极低。

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