• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人外周血淋巴细胞表面免疫球蛋白及免疫球蛋白亚单位的电泳研究

Electrophoretic study of immunoglobulins and immunoglobulin sub-units on the surface of human peripheral blood lymphocytes.

作者信息

Bert G, Massaro A L, Di Cossano D L, Maja M

出版信息

Immunology. 1969 Jul;17(1):1-6.

PMID:4183028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1455928/
Abstract

Treatment of human peripheral blood lymphocytes with a polyvalent antiserum to human immunoglobulins causes a reduction in the electrophoretic mobility of the cells. Treatment of the lymphocytes with antisera to κ and λ chains has a similar effect, but antisera to α, γ and μ chains are only effective in this way when all antisera are mixed together. These findings point to the presence of immunoglobulin molecules on the surface of peripheral blood lymphocytes and the results are discussed in terms of the possible representation of immunoglobulin sub-units on the lymphocyte surface.

摘要

用人免疫球蛋白多价抗血清处理人外周血淋巴细胞会导致细胞电泳迁移率降低。用κ链和λ链抗血清处理淋巴细胞有类似效果,但α链、γ链和μ链抗血清只有在全部混合在一起时才会以这种方式有效。这些发现表明外周血淋巴细胞表面存在免疫球蛋白分子,并根据淋巴细胞表面免疫球蛋白亚基的可能表现形式对结果进行了讨论。

相似文献

1
Electrophoretic study of immunoglobulins and immunoglobulin sub-units on the surface of human peripheral blood lymphocytes.人外周血淋巴细胞表面免疫球蛋白及免疫球蛋白亚单位的电泳研究
Immunology. 1969 Jul;17(1):1-6.
2
[Presence of lymphocytes containing immunoglobulins in the peripheral blood of immunized rabbits].[免疫兔外周血中含免疫球蛋白淋巴细胞的存在情况]
Boll Soc Ital Biol Sper. 1969 Jul 31;45(14):921-4.
3
Electrophoretic study of immunoglobulin on the lymphocyte surface.淋巴细胞表面免疫球蛋白的电泳研究。
Nature. 1968 Jun 15;218(5146):1078-9. doi: 10.1038/2181078a0.
4
[The formation of spontaneous rosettes by human lymphocytes of the peripheral blood].[外周血人淋巴细胞自发玫瑰花结的形成]
Folia Allergol (Roma). 1971 May-Jun;18(3):215-23.
5
Studies on rabbit lymphocytes in vitro. XIV. Fractionation of rabbit peripheral blood lymphocytes by antibody-coated polyacrylamide beads.兔淋巴细胞的体外研究。十四、用抗体包被的聚丙烯酰胺珠对兔外周血淋巴细胞进行分离
J Immunol. 1971 Nov;107(5):1302-13.
6
Immunoglobulin determinants on the lymphocytes of normal rabbits. I. Demonstration by the mixed antiglobulin reaction of determinants recognized by anti-gamma, anti-mu, anti-Fab and anti-allotype sera, anti-As4 and anti-As6.正常兔淋巴细胞上的免疫球蛋白决定簇。I. 通过混合抗球蛋白反应证明抗γ、抗μ、抗Fab、抗同种异型血清、抗As4和抗As6所识别的决定簇
Immunology. 1970 Mar;18(3):417-29.
7
[Immunotolerance and its production].[免疫耐受及其产生]
Arzneimittelforschung. 1969 Aug;19(8):1161-9.
8
A method for measuring different classes of human immunoglobulins specific for the penicilloyl group.一种用于测量对青霉噻唑基团具有特异性的不同类别的人免疫球蛋白的方法。
Immunology. 1971 Sep;21(3):547-56.
9
Studies on human peripheral blood lymphocytes in vitro. V. Biosynthesis of immunoglobulins.
J Immunol. 1968 Sep;101(3):458-68.
10
Immunoglobulins of the hamster. I. Antibody activity in four immunoglobulin classes.仓鼠的免疫球蛋白。I. 四种免疫球蛋白类别的抗体活性
J Immunol. 1970 May;104(5):1220-7.

引用本文的文献

1
Fluorometric studies on the binding of antilymphocyte serum to lymph node cells.抗淋巴细胞血清与淋巴结细胞结合的荧光研究。
Immunology. 1971 Sep;21(3):437-41.
2
Immune responses in vitro. IV. Suppression of primary M, G, and A plaque-forming cell responses in mouse spleen cell cultures by class-specific antibody to mouse immunoglobulins.体外免疫反应。IV. 用小鼠免疫球蛋白的类特异性抗体抑制小鼠脾细胞培养物中初级M、G和A斑块形成细胞反应。
J Exp Med. 1972 Mar 1;135(3):675-97. doi: 10.1084/jem.135.3.675.
3
Cell surface immunoglobulin. II. Isolation and characterization of immunoglobulin from mouse splenic lymphocytes.细胞表面免疫球蛋白。II. 从小鼠脾淋巴细胞中分离和鉴定免疫球蛋白。
J Exp Med. 1971 Jul 1;134(1):242-64. doi: 10.1084/jem.134.1.242.
4
Immunoglobulin light chain determinants on unstimulated and stimulated human blood lymphocytes, assayed by indirect immunofluorescence.通过间接免疫荧光法检测未刺激和刺激后的人血淋巴细胞上的免疫球蛋白轻链决定簇。
Immunology. 1971 Jun;20(6):1099-111.

本文引用的文献

1
Cellular antibodies in kidney homotransplantation.肾脏同种移植中的细胞抗体。
J Immunol. 1960 Nov;85:516-22.
2
Electrophoretic mobilities of antigen-stimulated lymph node cells.抗原刺激的淋巴结细胞的电泳迁移率。
Immunology. 1967 Jan;12(1):21-6.
3
Electrophoretic study of immunoglobulin on the lymphocyte surface.淋巴细胞表面免疫球蛋白的电泳研究。
Nature. 1968 Jun 15;218(5146):1078-9. doi: 10.1038/2181078a0.
4
Studies on rabbit lymphocytes in vitro. V. The induction of blast transformation with sheep antisera to rabbit IgG subunits.兔淋巴细胞的体外研究。V. 用羊抗兔IgG亚基抗血清诱导母细胞转化
J Exp Med. 1967 Feb 1;125(2):289-301. doi: 10.1084/jem.125.2.289.