人外周血淋巴细胞表面免疫球蛋白及免疫球蛋白亚单位的电泳研究
Electrophoretic study of immunoglobulins and immunoglobulin sub-units on the surface of human peripheral blood lymphocytes.
作者信息
Bert G, Massaro A L, Di Cossano D L, Maja M
出版信息
Immunology. 1969 Jul;17(1):1-6.
Treatment of human peripheral blood lymphocytes with a polyvalent antiserum to human immunoglobulins causes a reduction in the electrophoretic mobility of the cells. Treatment of the lymphocytes with antisera to κ and λ chains has a similar effect, but antisera to α, γ and μ chains are only effective in this way when all antisera are mixed together. These findings point to the presence of immunoglobulin molecules on the surface of peripheral blood lymphocytes and the results are discussed in terms of the possible representation of immunoglobulin sub-units on the lymphocyte surface.
用人免疫球蛋白多价抗血清处理人外周血淋巴细胞会导致细胞电泳迁移率降低。用κ链和λ链抗血清处理淋巴细胞有类似效果，但α链、γ链和μ链抗血清只有在全部混合在一起时才会以这种方式有效。这些发现表明外周血淋巴细胞表面存在免疫球蛋白分子，并根据淋巴细胞表面免疫球蛋白亚基的可能表现形式对结果进行了讨论。
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