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1
Electrophoretic mobilities of antigen-stimulated lymph node cells.抗原刺激的淋巴结细胞的电泳迁移率。
Immunology. 1967 Jan;12(1):21-6.
2
[Ultrastructural study in Wistar rats of lymph node behavior in tumoral invasion. I. Cell reactions towards the introduction of soluble antigens in inexperienced animals].[Wistar大鼠肿瘤侵袭中淋巴结行为的超微结构研究。I. 未接触过抗原的动物对可溶性抗原引入的细胞反应]
C R Seances Soc Biol Fil. 1970;164(12):2534-8.
3
Antibody formation against Vibrio cholerae by mesenteric lymph node cell transfer.通过肠系膜淋巴结细胞转移产生针对霍乱弧菌的抗体形成。
Immunology. 1966 Jul;11(1):59-65.
4
Cell electrophoretic studies on lymph node cells--possible existence of two populations.淋巴结细胞的细胞电泳研究——两种细胞群体可能的存在情况。
Immunology. 1971 Jul;21(1):1-9.
5
Vibriocidal activity, immune globulin producing cells and immune globulin levels in Theropithecus gelada after administration of a vibrio cholerae antigen.给予霍乱弧菌抗原后狮尾狒的杀弧菌活性、免疫球蛋白产生细胞及免疫球蛋白水平
Immunology. 1968 Mar;14(3):319-24.
6
In vitro studies on antibody production by lymph node cells using cell electrophoresis.利用细胞电泳对淋巴结细胞产生抗体进行的体外研究。
Immunology. 1967 Oct;13(4):433-9.
7
The plaque test for the demonstration of antibodies against the enterobacterial common antigen produced by spleen and lymph node cells.用于检测脾脏和淋巴结细胞产生的抗肠杆菌共同抗原抗体的蚀斑试验。
Immunology. 1967 Dec;13(6):539-45.
8
Local unresponsiveness to sheep erythrocytes in the popliteal lymph node of the guinea pig.豚鼠腘淋巴结对绵羊红细胞的局部无反应性
Ann Med Exp Biol Fenn. 1971;49(3):133-7.
9
Karyometric and autoradiographic studies of regional lymph node cells in rabbit after antigenic challenge.抗原刺激后兔局部淋巴结细胞的核测量和放射自显影研究。
Pol Med J. 1971;10(2):475-88.
10
Cytotoxic antibodies in rabbit anti-leukocyte serum: relation to suppression of transferred lymph node cells.兔抗白细胞血清中的细胞毒性抗体：与转移淋巴结细胞抑制的关系
J Immunol. 1967 Oct;99(4):721-8.

引用本文的文献

1
In vitro studies on antibody production by lymph node cells using cell electrophoresis.利用细胞电泳对淋巴结细胞产生抗体进行的体外研究。
Immunology. 1967 Oct;13(4):433-9.
2
Demonstration of sensitized lymphocytes in blood.血液中致敏淋巴细胞的检测
J Clin Pathol. 1971 Mar;24(2):179-81. doi: 10.1136/jcp.24.2.179.
3
On the mode of action of antilymphocytic serum: experiments on electrophoretic mobility of macrophages in experimental allergic encephalomyelitis.关于抗淋巴细胞血清的作用方式：实验性变应性脑脊髓炎中巨噬细胞电泳迁移率的实验
Clin Exp Immunol. 1970 Sep;7(3):395-400.
4
The detection by cellular electrophoresis of surface antibodies on human lymphocytes.通过细胞电泳检测人淋巴细胞表面抗体。
Clin Exp Immunol. 1969 Dec;5(6):669-72.
5
Cell electrophoretic studies on lymph node cells--possible existence of two populations.淋巴结细胞的细胞电泳研究——两种细胞群体可能的存在情况。
Immunology. 1971 Jul;21(1):1-9.
6
Immunological activity of blood lymphocyte fractions. A study by the macrophage electrophoretic mobility method.血液淋巴细胞组分的免疫活性。巨噬细胞电泳迁移率法研究。
Clin Exp Immunol. 1972 Apr;10(4):571-9.
7
A method of separating the lymph-node cells, of C57 BL mice allergized with BP8 ascites tumour, into two fractions with a fast and slow electrophoretic mobility: demonstration that only the "fast LNC" will protect C3H mice against challenge with the tumour.一种将用BP8腹水瘤致敏的C57 BL小鼠的淋巴结细胞分离成电泳迁移率快和慢的两个组分的方法：证明只有“快速淋巴结细胞”能保护C3H小鼠免受该肿瘤的攻击。
Br J Exp Pathol. 1972 Apr;53(2):111-24.
8
Delayed hypersensitivity studies: some applications of cell electrophoresis.迟发型超敏反应研究：细胞电泳的一些应用
J R Coll Physicians Lond. 1972 Apr;6(3):316-26.
9
Fluorometric studies on the binding of antilymphocyte serum to lymph node cells.抗淋巴细胞血清与淋巴结细胞结合的荧光研究。
Immunology. 1971 Sep;21(3):437-41.
10
Affinity of antigen for white cells and its relation to the induction of antibody formation.抗原与白细胞的亲和力及其与抗体形成诱导的关系。
Bacteriol Rev. 1968 Dec;32(4 Pt 2):404-24.

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抗原刺激的淋巴结细胞的电泳迁移率。

Electrophoretic mobilities of antigen-stimulated lymph node cells.

作者信息

Sundaram K, Phondke G P, Ambrose E J

出版信息

Immunology. 1967 Jan;12(1):21-6.

PMID:6017283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1409004/
Abstract

The effect of immunization against a bacterial antigen on electrophoretic mobility of lymph node cells has been studied. Incubation of non-stimulated lymph node cells with antigens altered their electrophoretic mobility. However, on washing the antigen away, the original mobility was regained. Antigen-stimulated lymph node cells had a lower electrophoretic mobility. It was further irreversibly reduced on incubation with the same antigen. This suggests the possibility of formation of firm antigen—antibody complexes at the cell surface. Implications of these findings and feasibility of using the technique of cell electrophoresis for the study of immune response at the cellular level is discussed.

摘要

已经研究了针对细菌抗原的免疫接种对淋巴结细胞电泳迁移率的影响。将未受刺激的淋巴结细胞与抗原一起孵育会改变其电泳迁移率。然而，洗去抗原后，又恢复了原来的迁移率。抗原刺激的淋巴结细胞具有较低的电泳迁移率。用相同抗原孵育后，其电泳迁移率进一步不可逆地降低。这表明在细胞表面可能形成了牢固的抗原-抗体复合物。讨论了这些发现的意义以及使用细胞电泳技术在细胞水平研究免疫反应的可行性。