De Cree J, Geukens H, Verhaegen H
MMW Munch Med Wochenschr. 1978 May 5;120(18):627-30.
31 patients with intermittent claudication were treated with 10 mg Flunarizine (Sibelium) daily for 6 months. Before the beginning of the trial and after a period of 6 months, a plethysmographic examination was undertaken to determine the reactive hyperemia elicited by a temporary arterial occlusion. 25 patients showed an improvement in at least one of the parameters measured during the reactive hyperemia. Lengthening of the walking distance was also seen at the same time in 24 of these patients. In a further analysis of our results it was shown that in each of the 25 patients those parameters of the reactive hyperemia improved which had deviated furthest from the normal.
31例间歇性跛行患者每日服用10毫克氟桂利嗪（西比灵），持续6个月。在试验开始前和6个月后，进行了体积描记法检查，以确定由暂时性动脉闭塞引起的反应性充血情况。25例患者在反应性充血期间测量的至少一项参数有所改善。其中24例患者同时出现步行距离延长。在对我们的结果进行进一步分析时发现，在这25例患者中，反应性充血的那些偏离正常最远的参数均得到了改善。
