表面电荷减少作为巨噬细胞识别从正成红细胞排出的细胞核的一种解释。
Reduction in surface charge as an explanation of the recognition by macrophages of nuclei expelled from normoblasts.
作者信息
Skutelsky E, Danon D
出版信息
J Cell Biol. 1969 Oct;43(1):8-15. doi: 10.1083/jcb.43.1.8.
Abstract
The density and distribution of electric charge on the surface of rabbit bone marrow cells was visualized by electron microscopy after the cell surfaces had been stained with charged colloidal iron particles. Expulsed erythroid nuclei are less negatively charged than any other cell in the bone marrow. They carry from about one-half to one-third of the charge density on the remaining future reticulocyte. The reduction in the surface charge density is already apparent when the nucleus is partially expulsed. Practically no positive charge was found on its surface or on the surface of any other bone marrow cell. The possibility that the reduced negative charge on the surface of expelled erythroid nuclei is one of the means by which the macrophage distinguishes it from other bone marrow cells is discussed.
摘要
在用带电的胶体铁颗粒对兔骨髓细胞表面进行染色后，通过电子显微镜观察到了细胞表面电荷的密度和分布。排出的红细胞核带负电荷的程度比骨髓中的任何其他细胞都要低。它们携带的电荷密度约为剩余未来网织红细胞的二分之一到三分之一。当细胞核部分排出时，表面电荷密度的降低就已经很明显了。在其表面或任何其他骨髓细胞的表面几乎没有发现正电荷。文中讨论了排出的红细胞核表面负电荷减少可能是巨噬细胞将其与其他骨髓细胞区分开来的方式之一。
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本文引用的文献
1
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Biochim Biophys Acta. 1964 May 25;79:606-17. doi: 10.1016/0926-6577(64)90227-x.
2
The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.在电子显微镜检查中，将高pH值的柠檬酸铅用作电子不透明染色剂。
J Cell Biol. 1963 Apr;17(1):208-12. doi: 10.1083/jcb.17.1.208.
3
[Embedding in polyester for ultrathin sections].[包埋于聚酯中用于超薄切片]
J Ultrastruct Res. 1958 Dec;2(2):200-14. doi: 10.1016/s0022-5320(58)90018-2.
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Rev Hematol. 1955;10(2):300-13; discussion, 324-44.
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Rev Hematol. 1952;7(3):407-35.
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