兔嗜同种细胞抗体上的重链和轻链同种异型标记
Heavy and light chain allotypic markers on rabbit homocytotropic antibody.
作者信息
Kindt T J, Todd C W
出版信息
J Exp Med. 1969 Oct 1;130(4):859-66. doi: 10.1084/jem.130.4.859.
Abstract
Evidence has been presented that rabbit homocytotropic antibody prepared against ovalbumin bears allotypic markers of both group a (heavy chain) and group b (light chain). This was shown by specific removal of activity in passive cutaneous anaphylaxis assays by anti-allotype immunoadsorbents. The homocytotropic antibody has properties which indicate that it belongs to a new class of rabbit immunoglobulin. These results demonstrate that this newly described class possesses the allotypes of both groups a and b, as has been previously shown for other rabbit immunoglobulin classes.
摘要
已有证据表明，针对卵清蛋白制备的兔亲同种细胞抗体带有a组（重链）和b组（轻链）的同种异型标记。这在被动皮肤过敏反应试验中通过抗同种异型免疫吸附剂特异性去除活性得以证明。亲同种细胞抗体具有表明它属于兔免疫球蛋白新类别的特性。这些结果证明，这一最新描述的类别拥有a组和b组的同种异型，正如先前对其他兔免疫球蛋白类别所显示的那样。
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