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粉尘螨的变应原和抗原。

Allergens and antigens of Dermatophagoides farinae.

作者信息

Holford-Strevens V, Wide L, Milne J F, Pepys J

出版信息

Clin Exp Immunol. 1970 Jan;6(1):49-59.

PMID:4190342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1712748/
Abstract

Extracts of cultured on Gaines dog-meal plus yeast, and in particular the `protein' fraction precipitated by ammonium sulphate, give stronger skin test reactions in house dust sensitive patients than extracts of and of house dust. Specific IgE was found against the extract in eighteen out of twenty house dust sensitive subjects. Precipitins were found in human sera against extracts of and house dust and also against antigens in cereal and vegetable dusts. These precipitin tests provided evidence of related antigens in extracts of house dust and and in extracts of house dust and , but not in and .

摘要

在加有酵母的盖恩斯犬粮上培养的提取物，特别是硫酸铵沉淀出的“蛋白质”部分，在对屋尘敏感的患者中引起的皮肤试验反应比[未提及的提取物1]提取物和屋尘提取物更强。在20名对屋尘敏感的受试者中，有18人发现了针对[未提及的提取物2]提取物的特异性IgE。在人血清中发现了针对[未提及的提取物2]和屋尘提取物以及谷物和蔬菜粉尘中抗原的沉淀素。这些沉淀素试验证明了屋尘与[未提及的提取物2]提取物之间以及屋尘与[未提及的提取物1]提取物之间存在相关抗原，但[未提及的提取物1]和[未提及的提取物2]之间不存在。

相似文献

1
Allergens and antigens of Dermatophagoides farinae.粉尘螨的变应原和抗原。
Clin Exp Immunol. 1970 Jan;6(1):49-59.
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House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program.在儿童哮喘管理项目中，接触屋尘螨和蟑螂是皮肤过敏试验呈阳性反应的强烈风险因素。
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[Antigenic identity of house dust with the house dust mite. 1. Clinical evaluation of dermatophagoides farinae, Hughes, 1961 (Acarina psoroptidae)].[屋尘与屋尘螨的抗原一致性。1. 粉尘螨（休斯，1961年）（疥螨科螨类）的临床评估]
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Antigenic relation between house dust and a dust mite, Dermatophagoides farinae Hughes, 1961, by a fractionation method.采用分级分离法研究屋尘与一种尘螨（1961年休斯命名的粉尘螨）之间的抗原关系。
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[Correlation between the prick test and specific IgE against allergens of house dust and Dermatophagoides sp].[点刺试验与针对屋尘和尘螨变应原的特异性IgE之间的相关性]
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引用本文的文献

1
Antigens and allergens in Dermatophagoïdes farinae mite. I. Immunochemical and physicochemical study of two allergenic fractions from a partially-purified Dermatophagoïdes farinae mite extract.粉尘螨中的抗原和变应原。I. 来自部分纯化的粉尘螨提取物的两种变应原组分的免疫化学和物理化学研究。
Immunology. 1981 Oct;44(2):239-47.
2
Antigens and allergens in Dermatophagoïdes farinae mite. II. Purification of AG f1, a major allergen in Dermatophagoïdes farinae.粉尘螨中的抗原和变应原。II. 粉尘螨主要变应原AG f1的纯化。
Immunology. 1982 Aug;46(4):679-87.
3
Mites and house dust allergy.螨虫与屋尘过敏。
Br Med J. 1971 Jun 12;2(5762):601-2.
4
'False positive' precipitation reactions to extracts of organic dusts due to a teichoic acid from S. aureus. Techniques.由金黄色葡萄球菌的磷壁酸导致的对有机粉尘提取物的“假阳性”沉淀反应。技术。
Clin Exp Immunol. 1970 Dec;7(6):897-902.
5
Isolation of a potent allergen from house dust mite by interaction with the lectin tridacnin.
Experientia. 1976 May 15;32(5):641-4. doi: 10.1007/BF01990210.
6
Measurement of IgG, IgA and IgE antibodies to Dermatophagoides pteronyssinus by antigen-binding assay, using a partially purified fraction of mite extract (F4P1).使用螨提取物的部分纯化级分（F4P1），通过抗原结合试验测定针对屋尘螨的IgG、IgA和IgE抗体。
Clin Exp Immunol. 1978 Oct;34(1):126-36.

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