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痘苗病毒对同步化猪肾细胞的感染

Vaccinia virus infection of synchronized pig kidney cells.

作者信息

Groyon R M, Kniazeff A J

出版信息

J Virol. 1967 Dec;1(6):1255-64. doi: 10.1128/JVI.1.6.1255-1264.1967.

DOI:10.1128/JVI.1.6.1255-1264.1967
PMID:4192871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC375416/
Abstract

Vaccinia virus replication was studied in pig kidney (PK-15) cells synchronized by excess thymidine treatment. It was found that virus replication with concomitant inhibition of mitosis can occur at any period in the life cycle of the cell except for the narrow span of time from late prophase through telophase. Cells infected at this time continue to divide, and vaccinia does not replicate until cell division is complete.

摘要

在通过过量胸苷处理同步化的猪肾（PK-15）细胞中研究了痘苗病毒的复制。结果发现，伴随有丝分裂抑制的病毒复制可发生在细胞生命周期的任何时期，但从晚前期到末期的狭窄时间段除外。此时感染的细胞继续分裂，痘苗病毒直到细胞分裂完成才开始复制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/5bf94c87e34f/jvirol00330-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/b308e9596f03/jvirol00330-0157-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/d06ad2530b14/jvirol00330-0158-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/26aef5b3dd3a/jvirol00330-0160-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/5bf94c87e34f/jvirol00330-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/b308e9596f03/jvirol00330-0157-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/d06ad2530b14/jvirol00330-0158-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/26aef5b3dd3a/jvirol00330-0160-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09c/375416/5bf94c87e34f/jvirol00330-0161-a.jpg

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Phasing, Mitotic Delay, and Chromosomal Aberrations in Mammalian Cells.哺乳动物细胞中的相位、有丝分裂延迟和染色体畸变
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