Nesterin M F, Markelova V F, Liapkov B G, Listratenkova E F, Narodetskaia R V
Vopr Pitan. 1979 Jan-Feb(1):32-6.
In tests conducted on rats the process of eliminating the endogenous formed lipids with bile was studied and the discovered changes were contrasted against the lipids metabolism disorders in the liver and blood of the animals receiving rations with differing quantitative and qualitative content of carbohydrates. A balanced ration with saccharose led to a higher quantity and radioactivity of the total lipids and triglycerides in the liver and blood. In the bile a fall in the level of the cholic acid, cholesterol and the lipid complex and an increased radioactivity in the composition of the lipids complex, cholesterol and phospholipids were observed. A ration with an elevated level of starch did not upset the lipids metabolism in the liver and blood. In the bile the lipids complex decreased, the quantity of cholic acid increased, while the radioactivity in the lipids complex and phospholipids was rising. A carbohydrate-rich ration with saccharose raised the content of total lipids, triglycerides and of the ether-bound blood cholesterol and their radioactivity. The described diet resulted in an increased amount of the bile and in a drop therein of the level of the lipids complex, cholesterol and phospholipids and in an accrued radioactivity in them.
在对大鼠进行的试验中,研究了用胆汁消除内源性生成脂质的过程,并将发现的变化与食用碳水化合物数量和质量不同的日粮的动物肝脏和血液中的脂质代谢紊乱情况进行了对比。含有蔗糖的均衡日粮导致肝脏和血液中总脂质和甘油三酯的数量及放射性增加。在胆汁中,观察到胆酸、胆固醇和脂质复合物水平下降,脂质复合物、胆固醇和磷脂组成中的放射性增加。淀粉含量升高的日粮并未扰乱肝脏和血液中的脂质代谢。在胆汁中,脂质复合物减少,胆酸数量增加,而脂质复合物和磷脂中的放射性上升。富含蔗糖的碳水化合物日粮提高了总脂质、甘油三酯和醚结合血胆固醇的含量及其放射性。所述饮食导致胆汁量增加,其中脂质复合物、胆固醇和磷脂水平下降,且它们的放射性增加。