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[使用低蛋白含量且碳水化合物与脂肪比例各异的饮食时肝脏、血液和胆汁中的脂质代谢指标]

[Lipid metabolic indices in the liver, blood and bile while using diets with a low protein content and varying carbohydrate and fat ratio].

作者信息

Nesterin M F, Markelova V F, Listratenkova E F, Narodetskaia R V, Liapkov B G

出版信息

Vopr Pitan. 1979 May-Jun(3):44-8.

PMID:462892
Abstract

In tests with rats observations over changes in the lipids metabolism in the liver, blood and bile with application of low-protein diets and different proportions of carbohydrates and fat were carried out. The No-1 ration containing 5 per cent of protein and an augmented to 70 per cent carbohydrates (starch) amount led to accumulation in the liver and to increased radioactivity in triglycerides and ether-bound cholesterol, to diminution of the amount and radioactivity of phospholipids in the liver and blood and to a lowered lipids complex concentration in the bile of cholic acid and proportions of glycoconjugates and tauroconjugates. The No-2 ration, where a greater carbohydrates quota was represented by a mixture of starch and saccharose, and also the No-3 ration with an elevated share of fat, produced similar, but to a higher degree, pronounced changes in the liver, blood and bile.

摘要

在用大鼠进行的试验中,观察了低蛋白饮食以及不同碳水化合物与脂肪比例对肝脏、血液和胆汁脂质代谢变化的影响。1号日粮含5%的蛋白质,碳水化合物(淀粉)含量增至70%,导致肝脏中脂质蓄积,甘油三酯和醚酯型胆固醇放射性增加,肝脏和血液中磷脂的量和放射性减少,胆汁中胆酸、糖缀合物和牛磺缀合物比例组成的脂质复合物浓度降低。2号日粮中,较大比例的碳水化合物由淀粉和蔗糖混合物构成,3号日粮脂肪比例较高,二者均在肝脏、血液和胆汁中产生了类似但程度更显著的变化。

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